Clomipramine is used to deal with obsessive compulsive disorder (OCD). It helps decrease persistent/unwanted thoughts (obsessions), and it assists in easing the urge to perform repeated tasks (compulsions such as hand-washing, counting, checking) that interfere with everyday living.
This medication belongs to a course of medicines called tricyclic antidepressants. It works by restoring the balance of certain substances that are naturalserotonin, and others) in the brain.
OTHER USES: This area contains uses with this drug being maybe not placed in the approved professional labeling for the drug but that could be prescribed by the health care professional. Make use of this medication for a condition that is listed in this section only if it has been so prescribed by the health care professional.
This medication has additionally been utilized to treat depression, panic attacks, and pain that is ongoing.
Read the Medication Guide available from your pharmacist. Consult your pharmacist or doctor if you have any questions.
Take this medication by mouth with or without meals as directed by your medical professional. To minimize side-effects such as stomach upset, clomipramine may be started at a low dose, given in several doses during the day with meals, and slowly increased as your body gets used to it. After you have reached the best dose for you, the total dose can be taken once daily, usually at bedtime to prevent daytime drowsiness or as directed by your doctor. Usually, the dose that is daily not be more than 250 milligrams for grownups and 200 milligrams for kiddies and teenagers.
Follow your doctor's instructions very carefully. Never just take just about medication or take it more frequently than prescribed. Your condition will not improve any faster and your risk of adverse effects such as for example seizures may be increased. Dosage is dependant on your medical condition and response to therapy.
Avoid eating grapefruit or drinking grapefruit juice while being treated with this medication unless your doctor instructs you otherwise. Grapefruit can increase the amount of certain medications in your bloodstream. Consult your doctor or pharmacist for additional information.
Use this medication regularly in purchase to have the benefit that is most from it. Continue to take it even if you feel well. To help you remember, use it at the same time(s) each time.
Usually do not suddenly stop using this medication without consulting your doctor. Some conditions may be even worse when the drug is abruptly stopped. You could experience sweating, dizziness, nausea, vomiting, headache, or irritability if you suddenly stop taking this drug. Your dose may gradually need to be decreased.
It might simply take 2 to 3 weeks or longer ahead of the full aftereffects of this medication are noticed. Inform your doctor if for example the condition persists or if it worsens.
See also Warning section.
Dizziness, drowsiness, dry lips, constipation, stomach upset, nausea, vomiting, changes in appetite/weight, flushing, sweating, tiredness and blurred vision may occur. Anxiety symptoms may temporarily worsen when you first start taking clomipramine. If any of these effects persist or worsen, notify your doctor or pharmacist immediately.
To ease mouth that is dry suck on (sugarless) hard candy or ice chips, chew (sugarless) gum, drink water or utilize a saliva substitute.
To avoid constipation, maintain a meal plan adequate in fiber, drink plenty of water, and workout. If you become constipated while by using this drug, consult your pharmacist for assist in selecting a laxative (age.g., stimulant-type with stool softener).
Understand that your doctor has recommended this medication she has judged that the benefit to you is greater than the risk of side effects because he or. Many people using this medication do not have adverse that is serious.
Tell your physician right away if some of these unlikely but adverse that is serious occur: mental/mood changes (e.g., confusion, despair, memory problems), enlarged/painful breasts, unwanted breast milk manufacturing, irregular/painful menstrual durations, muscle mass stiffness, ringing within the ears, sexual problems (e.g., reduced sexual ability, changes in desire), shakiness (tremors), numbness/tingling associated with the hands/feet, trouble urinating.
Tell your physician straight away if any of these rare but very serious side effects occur: easy bruising/bleeding, signs of infection (e.g., fever, persistent sore throat), unusual/uncontrolled motions (especially associated with tongue/face/lips), serious stomach/abdominal pain, dark urine, yellowing of eyes/skin.
This medication may increase serotonin and hardly ever cause a very condition that is serious serotonin syndrome/toxicity. The risk increases you take if you are also taking other drugs that increase serotonin, so tell your doctor or pharmacist of all the drugs. Get medical help right away in the event that you develop a number of the following symptoms: fast heartbeat, hallucinations, loss of coordination, severe dizziness, severe nausea/vomiting/diarrhea, twitching muscle tissue, unexplained fever, unusual agitation/restlessness.
Get medical help right away if you have any very severe part effects, including: black stools, chest discomfort, fainting, slow/fast/irregular heartbeat, seizures, vomit that looks like coffee grounds, eye pain/swelling/redness, vision changes (such as seeing rainbows around lights through the night).
An extremely severe allergic reaction to this drug is unlikely, but seek immediate medical attention if it occurs. Symptoms of a serious reaction that is allergic: rash, itching/swelling (especially regarding the face/tongue/throat), severe dizziness, difficulty breathing.
This is not a complete list of possible side effects. If you notice other effects not listed above, contact your pharmacist or doctor.
In the usa -
Phone your medical professional for medical advice about side effects. You may report effects that are side FDA at 1-800-FDA-1088 or at www.fda.gov/medwatch.
In Canada - Call your medical professional for medical advice about unwanted effects. You may report effects that are side Health Canada at 1-866-234-2345.
Before taking clomipramine, tell your doctor or pharmacist if you have any other allergies if you are allergic to it; or to other tricyclic antidepressants (e.g., imipramine, nortriptyline); or. This product may contain ingredients that are inactive which can cause allergic reactions or other dilemmas. Speak to your pharmacist for more details.
Before applying this medication, tell your doctor or pharmacist your health background, especially of: blood dilemmas (e.g., purpura, thrombocytopenia), difficulty in breathing (age.g., asthma, chronic bronchitis), individual or genealogy of glaucoma (angle-closure type), eating disorders (e.g., bulimia), heart dilemmas (e.g., arrhythmias, coronary artery disease, recent heart attack), intestinal dilemmas (e.g., chronic constipation, ileus), liver problems, kidney issues, personal or genealogy of other mental/mood conditions (e.g., manic depression, schizophrenia), history of hospitalization for a very severe response to certain medications (neuroleptic malignant problem), heartburn/stomach acid in the esophagus (e.g., due to hiatal hernia), seizures, overactive thyroid (hyperthyroidism), trouble urinating (urinary retention, enlarged prostate), any condition that may boost your risk of seizures (e.g., alcohol/sedative dependency, use of electroconvulsive therapy, mind injury/disease), specific types of tumors (e.g., pheochromocytoma, neuroblastoma).
Clomipramine may cause an ailment that affects the heart rhythm (QT prolongation). QT prolongation can seldom cause serious (rarely fatal) fast/irregular heartbeat and other symptoms (such as severe dizziness, fainting) that want medical help right away.
The risk of QT prolongation can be increased if you have certain medical conditions or are using other drugs that could cause QT prolongation. Before using clomipramine, inform your doctor or pharmacist of all the drugs you are taking and in case you have any of the following conditions: certain heart problems (heart failure, slow heartbeat, QT prolongation in the EKG), family history of certain heart problems (QT prolongation in the EKG, sudden cardiac death).
Low levels of potassium or magnesium in the blood may increase your risk also of QT prolongation. This risk may increase if you have conditions such as severe sweating, diarrhea, or vomiting if you use certain drugs (such as diuretics/"water pills") or. Talk to your medical practitioner about using clomipramine safely.
This drug could make you dizzy or drowsy or cause temporary blurred vision. Do not drive, use machinery, or do any activity that requires alertness or clear vision you can perform such activities safely until you are sure. Limit beverages that are alcoholic.
To diminish dizziness and lightheadedness, get up slowly when increasing from a seated or lying position.
Before having surgery, tell your doctor or dentist that you're taking this medication.
Care is recommended when utilizing this drug in children whom be involved in active activities since it may increase the possibility of heart problems. (See also the Warning section.)
Older adults may be more delicate to your relative adverse effects of this drug, especially bleeding, confusion, dizziness, and QT prolongation (see above).
This medication should be used only when plainly needed during pregnancy. Newborns exposed to clomipramine during pregnancy might experience withdrawal symptoms or side effects. Tell your doctor right away if you notice jitteriness, shaking, feeding problems, fast breathing, or seizures in your newborn.
Since untreated mental/mood issues (such as for instance obsessive compulsive disorder, depression, panic attack) can be a serious condition, do not stop taking this medication unless directed by your doctor. If you are planning pregnancy, become pregnant, or think you may be pregnant, immediately discuss with your doctor the benefits and risks of using this medication during pregnancy.
This medication passes into breast milk and could have undesirable effects on a nursing baby. Consult with your doctor before breast-feeding.
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