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ARAVA is indicated in adults for that treating active arthritis rheumatoid (RA):


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Take this medicine only as directed by your doctor. Do not take really it, do not take on it often, and do not take it much more time than your physician ordered.

The dose of the medicine will be different for various patients. Follow a medical expert's orders or directions on the label. The following information includes merely the average doses with this medicine. If your dose is unique, usually do not change it unless a medical expert informs you to do so.

The amount of medicine that you take depends about the strength in the medicine. Also, the quantity of doses you are taking every day, the time allowed between doses, and also the time period you are taking the medicine depend about the disease you simply are choosing the medicine.

For oral dosage form (tablets):

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For rheumatism:

If you miss a dose on this medicine, take it immediately. However, whether it is almost time for your forthcoming dose, skip the missed dose and return to your family dosing schedule. Do not double doses.

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Store at 25°C (77°F); excursions able to 15-30°C (59-86°F). Protect from light. Keep out in the reach of children. Do not keep outdated medicine or medicine will no longer needed. Store the medicine in a very closed container at room temperature, far from heat, moisture.

 Keep out of the reach of kids. Do not keep outdated medicine or medicine don't needed. Store the medicine in a very closed container at room temperature, from heat, moisture.


Side Effects

Stop by using this medicine and check with your physician straight away if you're having burning, numbness, tingling, or painful sensations inside the arms, hands, legs, or feet. These could be symptoms of a condition called peripheral neuropathy.

Adverse reactions linked to the usage of leflunomide in RA include diarrhea, elevated liver enzymes (ALT and AST), alopecia and rash.

Along featuring its needed effects, medication may cause some unwanted side effects. Although not many of these side effects may occur, whenever they do occur they may need medical assistance.

Check with a medical expert immediately if any of the following side effects occur:
More common
Bloody or cloudy urine
difficult or painful breathing
difficult, burning, or painful urination
frequent urge to urinate
decrease of appetite
feeling sick
sore throat
tightness within the chest
yellow eyes or skin
Less common
Burning feeling inside the chest or stomach
burning, prickling, or tingling sensation inside the fingers or toes
chest pain
fast heartbeat
joint or muscle pain or stiffness
pounding heartbeat
severe stomach pain
lack of breath
tenderness within the stomach area
unusual tiredness or weakness
Incidence mysterious
Area rash
black or tarry stools
bleeding gums
blistering, peeling, or loosening from the skin
blood in the stools
burning, numbness, tingling, or painful sensations
clay-colored stools
continuing vomiting
cough or hoarseness
dark urine
fever with or without chills
general a feeling of tiredness or weakness
high fever
large, hive-like swelling around the face, eyelids, lips, tongue, throat, hands, legs, feet, or sex organs
light-colored stools
lower back or side pain
pains within the stomach, side, or abdomen, possibly radiating to the back
pale skin
pinpoint red spots on the skin
rapid, shallow breathing
red lesions on the skin, often having a purple center
red, irritated eyes
sores, ulcers, or white spots inside the mouth or around the lips
swollen glands
unexplained bleeding or bruising
unpleasant breath odor
unsteadiness or awkwardness
unusual bleeding or bruising
upper right abdominal or stomach pain
vomiting of blood
weakness inside the arms, hands, legs, or feet

Some unwanted side effects may occur very often tend not to need medical help. These negative effects might go away during treatment since your body adjusts on the medicine. Also, your wellbeing care professional might be able to share with you methods to prevent or reduce a few of these negative effects. Check along with your health care professional if any from the following unwanted effects continue or are bothersome or if you might have any queries about them:
More common
Back pain
hair loss
skin rash
stomach pain
weight loss (unexplained)
Less common
decreased appetite
dry mouth
irritation or soreness in the mouth
itching in the skin
pain or burning inside the throat
runny nose

Other unwanted effects unlisted may also occur in some patients. If you notice some other effects, check using your healthcare professional.

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It is vital that your physician look at your progress at regular visits to ensure that this prescription medication is working properly. Blood tests are usually necesary to test for uncomfortable side effects.

Using this medicine when you are pregnant can harm your baby. Use an effective form of birth control method to maintain from having a baby. If you think you have get pregnant while using the medicine, tell your physician without delay.

Leflunomide can also cause birth defects when the father is using it when his sexual partner becomes pregnant. Men taking leflunomide should use condoms like a way of birth control during intercourse. A man planning to father a youngster should stop taking this medicine and check regarding his doctor straight away.

Serious skin reactions can take place using this type of medicine. Stop applying this medicine and appearance with a medical expert right away if you might have any with the following symptoms while investing in this medicine: blistering, peeling, or loosening with the skin; chills; itching; joint or muscle pain; red lesions on the skin, often having a purple center; sores, ulcers, or white spots inside mouth or about the lips; or unusual tiredness or weakness.

Liver problems may occur while you are choosing this medicine. Stop applying this medicine and look with your physician immediately if you're having several of the symptoms: abdominal or stomach pain or tenderness; clay-colored stools; dark urine; decreased appetite; fever; headache; loss of appetite; nausea or vomiting; skin rash; swelling from the feet or legs; unusual tiredness or weakness; or yellow eyes or skin.

Leflunomide can temporarily lower the volume of white blood cells inside your blood, increasing the chance of getting contamination. It can also lower the number of platelets, that happen to be essential for proper blood clotting. If this occurs, there are certain precautions you'll be able to take, especially when your blood count is low, to cut back the risk of infection or bleeding:

Check with your doctor straight away if you've a cough with or without a fever, difficulty breathing, or any risk with breathing.

You have to have a skin test for tuberculosis prior to starting by using this medicine. Tell your physician if you or anyone within your home has ever had a confident response to a tuberculosis test.

Using this medicine may improve your likelihood of getting serious infections or cancer. Talk to your medical professional if you have concerns relating to this risk.

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Do not take other medicines unless they have been discussed with a medical expert. This includes prescription or nonprescription (over-the-counter [OTC]) medicines and herbal or nutritional vitamin supplements.

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