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Duloxetine is employed to deal with depression and anxiety. In addition, duloxetine is employed to simply help relieve nerve pain (peripheral neuropathy) in people with diabetes or ongoing pain due to health conditions such as for instance arthritis, chronic right back pain, or fibromyalgia (a condition that causes widespread discomfort).

Duloxetine may improve your mood, rest, appetite, and vitality, and decrease nervousness. It may also relieve pain due to certain conditions that are medical. Duloxetine is known as a serotonin-norepinephrine reuptake inhibitor (SNRI). This medication works by helping to restore the balance of certain natural substances (serotonin and norepinephrine) in mental performance.

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OTHER USES: This part contains uses of this medication which are perhaps not listed in the approved labeling that is professional the medication but that could be prescribed by your quality of life care expert. Utilize this medication for an ailment that is placed in this part only if it's been therefore recommended by your health care professional.

This medication may also be used to help treat other painful nerve conditions (neuropathic pain).

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Read the Medication Guide and, if available, the Patient Information Leaflet given by your pharmacist before you start using duloxetine and each time you get a refill. If you have any relevant questions, ask your doctor or pharmacist.

Take this medication by mouth as directed by your medical practitioner, usually 1 or 2 times a day with or without food. If you have nausea, it may help to take this drug with food. Swallow the capsule whole. Don't crush or chew the capsule or mix the contents with food or liquid. Doing therefore can release most of the drug at once, increasing the risk of adverse effects.

The dosage is dependant on your age, medical condition and response to treatment. To cut back your risk of part effects, your doctor may direct you to definitely start this medicine at a low dose and gradually increase your dose. Follow your doctor's instructions carefully. Take this medication regularly to get the benefit that is most from it. To aid you remember, take it during the same time(s) each time.

You should carry on taking this medicine as prescribed even should you feel well. Do not stop taking this medicine without consulting your doctor. Some conditions may become worse when this drug is abruptly stopped. Also, you may experience symptoms such as dizziness, confusion, mood swings, frustration, tiredness, diarrhea, sleep changes, and brief emotions similar to electric shock. Your dose may need to be gradually decreased to reduce side effects. Report any brand new or worsening symptoms right away.

Inform your doctor in case your condition persists or worsens.

Part Effects

See section that is also warning.

Nausea, dry mouth, constipation, loss of appetite, tiredness, drowsiness, or increased sweating may occur. If some of these results persist or aggravate, tell your medical professional immediately.

Dizziness or lightheadedness might occur, especially once you first start or increase your dose of this drug. To reduce the risk of dizziness, lightheadedness, or falling, get up slowly when rising from a sitting or lying position.

Remember that your medical practitioner has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of adverse effects. Many people using this medication do not have adverse that is serious.

This medicine may raise your blood pressure. Check your blood pressure regularly and tell your doctor if the total email address details are high.

Tell your doctor right away if some of these serious side impacts occur: confusion, easy bruising/bleeding, decreased interest in intercourse, alterations in intimate ability, muscle tissue cramps/weakness, shaking (tremor), difficulty urinating, unusual decrease into the amount of urine, signs of liver problems (such as stomach/abdominal pain, persistent sickness, vomiting, yellowing eyes/skin, dark urine).

Get medical help immediately if you have got any really severe unwanted effects, including: black/bloody stools, vomit that appears like coffee grounds, seizure, attention pain/swelling/redness, vision changes (such as for instance seeing rainbows around lights at night, blurred vision).

This medication may increase serotonin and rarely cause a very condition that is serious serotonin syndrome/toxicity. The risk increases you take (see Drug Interactions section) if you are also taking other drugs that increase serotonin, so tell your doctor or pharmacist of all the drugs. Get medical help right away if you develop a few of the next symptoms: fast heartbeat, hallucinations, loss of coordination, severe dizziness, serious nausea/vomiting/diarrhea, twitching muscle tissue, unexplained temperature, unusual agitation/restlessness.

a very serious reaction that is allergic this drug is rare. However, get help that is medical away if you notice any symptoms of a serious allergic response, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, difficulty respiration, skin blisters, mouth sores.

This is certainly not a complete list of possible side effects. If you notice other effects not listed above, contact your pharmacist or doctor.

In the US -

Call your doctor for medical advice about part effects. You may report effects that are side FDA at 1-800-FDA-1088 or at

In Canada - Phone your doctor for medical advice about part effects. You may possibly report side effects to Health Canada at 1-866-234-2345.


Before using duloxetine, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain ingredients that are inactive that may cause allergic reactions or other dilemmas. Speak to your pharmacist for lots more details.

Before making use of this medication, tell your doctor or pharmacist your medical history, especially of: personal or family history of psychiatric disorders (such as for example bipolar/manic-depressive disorder), personal or family history of suicide attempts, bleeding issues, personal or household history of glaucoma (angle-closure type), hypertension, renal disease, liver disease, seizure condition, stomach dilemmas (such as slow emptying for the stomach), use/abuse of alcohol.

This drug might make you dizzy or drowsy. Do not drive, use machinery, or do any activity that requires alertness until you are sure you can perform such activities safely. Avoid beverages that are alcoholic.

When you yourself have diabetes, duloxetine may impact your blood sugar levels. Check always your blood sugar levels frequently as directed by your doctor. Your medical professional may need to regulate your diabetes medication, workout program, or diet.

Before having surgery, tell your doctor or dentist about most of the services and products you employ (including prescription drugs, nonprescription medications, and herbal products).

Older adults may be more sensitive to the relative side effects of this drug, especially bleeding, dizziness, lightheadedness, or loss of coordination. Older adults may also be more likely to develop a type of salt imbalance (hyponatremia), especially if they are taking "water pills" (diuretics). Dizziness, lightheadedness, or loss of coordination can raise the risk of falling.

Kiddies may be more delicate to the relative side effects of this drug, especially loss of appetite and weight loss. Monitor height and weight in children who are taking this drug. See also Warning.

During pregnancy, this medication should really be used only if clearly needed. It may harm an unborn baby. Also, babies born to mothers who have used this drug during the last 3 months of pregnancy may develop withdrawal symptoms rarely such as feeding/breathing difficulties, seizures, muscle stiffness, or constant crying. If you notice any one of these symptoms in your newborn, tell the doctor promptly.

Since untreated mental/mood problems (such as despair, anxiety) could be a serious condition, do not stop taking this medication unless directed by your doctor. You may be pregnant, immediately discuss the benefits and risks of using this medication during pregnancy with your doctor if you are planning pregnancy, become pregnant, or think.

This drug passes into breast milk and could have effects that are undesirable a nursing infant. Check with your medical practitioner before breast-feeding.

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