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INDICATIONS

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Detrol is indicated to the treating overactive bladder with symptoms of urge urinary incontinence, urgency, and frequency.

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INSTRUCTIONS

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Take Detrol exactly as prescribed by your doctor. Do not take in larger or smaller amounts and for more than recommended. Follow the directions on the prescription label.

Your doctor may occasionally improve your dose to successfully receive the best results.

Take Detrol with water. Do not crush, chew, break, or open a controlled-release capsule. Swallow it whole. Breaking or opening the pill might cause excessive drug to be removed in the past.

Store Detrol at room temperature far from moisture and heat.

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If you missed a dose - take the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to create in the missed dose.

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DOSAGE

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The recommended dose of Detrol Capsules is 4 mg once daily with water and swallowed whole. The dose could be lowered to 2 mg daily according to individual response and tolerability; however, limited efficacy data are for sale to Detrol 2 mg.

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For patients with mild to moderate hepatic impairment (Child-Pugh Class A or B) or severe renal impairment (CCr 10-30 mL/min), the recommended dose of Detrol is 2 mg once daily. Detrol isn't recommended for used in patients with severe hepatic impairment (Child-Pugh Class C). Patients with CCKlO mL/min weren't studied and employ of Detrol on this population is not recommended.

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For patients who're taking drugs which might be potent inhibitors of CYP3A4 [e.g., ketoconazole, clarithromycin, ritonavir], the recommended dose of Detrol is 2 mg once daily.

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STORAGE

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Store Detrol at 77 degrees F (25 degrees C). Brief storage at temperatures between 59 and 86 degrees F (15 and 30 degrees C) is permitted. Store far from heat, moisture, and light-weight. Do not store within the bathroom. Keep Detrol out from the reach of kids and from pets.

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Side Effects

Get emergency medical help if you have these signs and symptoms of a hypersensitivity to Detrol: hives; breathlessness; swelling of your respective face, lips, tongue, or throat. Stop using Detrol and call your doctor simultaneously when you have all of these serious side effects:

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Less serious Detrol side effects can include:

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This is just not a complete report on negative effects and others may occur. Call your doctor for health advice about side effects.

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Precautions

Before taking tolterodine, tell your doctor or pharmacist in case you are allergic with it; or in case you have any other allergies. This product might have inactive ingredients, which may cause allergies and other problems. Talk to your pharmacist for more information.

This medication shouldn't be used in case you have certain medical conditions. Before applying this medicine, consult your medical professional or pharmacist for those who have: problems emptying your bladder (urinary retention), severe blockage of stomach/intestines (gastric retention), a particular eye condition (uncontrolled narrow-angle glaucoma).

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Before applying this medication, tell a medical expert or pharmacist your history, especially of: other bladder problems (e.g., bladder outflow obstruction), stomach/intestinal disease (e.g., ulcerative colitis), slowed movement of stomach/intestines, severe constipation, controlled narrow-angle glaucoma, kidney disease, liver disease, enlarged prostate, a particular muscle disease (myasthenia gravis).

Tolterodine could cause a disorder that affects the heart rhythm (QT prolongation). QT prolongation can infrequently lead to serious (rarely fatal) fast/irregular heartbeat as well as other symptoms (for example severe dizziness, fainting) which need immediate medical help. The probability of QT prolongation might be increased in case you have certain health conditions or are taking other drugs that will affect the heart rhythm (see also Drug Interactions section). Before using tolterodine, tell your physician or pharmacist if you have any of these conditions: certain cardiovascular disease (heart failure, slow heartbeat, QT prolongation in the EKG), genealogy and family history of certain heart disease (QT prolongation inside EKG, sudden cardiac death).

Low numbers of potassium or magnesium inside the blood may also increase your likelihood of QT prolongation. This risk may increase if you use certain drugs (for example diuretics/"water pills") or if you have conditions including severe sweating, diarrhea, or vomiting. Talk to your physician about using tolterodine safely.

This drug may make you dizzy or drowsy or cause blurred vision. Do not drive, use machinery, or go activity that will need alertness or clear vision until you are sure you are able to perform such activities safely. Limit alcohol consumption.

This medication could cause decreased sweating. Avoid becoming overheated in warm weather, saunas, or during exercise or other strenuous activities since heatstroke may occur.

Kidney function declines when you age. This medication is removed through the kidneys. Therefore, seniors could possibly be more understanding of this drug.

This medication needs to be used only when clearly needed during pregnancy. It is just not known whether Detrol will harm an unborn baby. Tell your medical professional in case you are pregnant or prefer to conceive while using this medication. Discuss the hazards and benefits with your medical professional.

It is unknown if this type of drug passes into breast milk. Consult your physician before breast-feeding.

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