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This medication is used to treat mental/mood problems such as depression. It may help improve mood and feelings of well-being, relieve anxiety and tension, help you sleep better, and increase your time level. This medication belongs to a class of medicines called tricyclic antidepressants. It works by affecting the balance of certain chemicals that are naturalneurotransmitters particularly serotonin) into the brain.

DIFFERENT USES: This section contains uses of this medication that are not placed in the approved professional labeling for the medication but that may be prescribed by your wellbeing care pro. Utilize this drug for a state of being which is listed in this section just if it's been so recommended by your medical care professional.

This medication might also be used to treat nerve discomfort (such as peripheral neuropathy, postherpetic neuralgia), consuming disorder (bulimia), other mental/mood dilemmas (such as anxiety, panic disorder), or to stop migraine headaches.

Just how to use Endep

Read the Medication Guide provided by your pharmacist before you start taking amitriptyline and each time you get a refill. If you have any relevant concerns, check with your medical practitioner or pharmacist.

Simply take this medication by mouth, often 1 to 4 times daily or as directed by your medical professional. If you take it only once a day, take it at bedtime to help reduce daytime sleepiness. The dosage is based on your condition that is medical and to therapy.

To reduce your risk of side results (such as for instance drowsiness, dry mouth, dizziness), your doctor may direct one to start this medicine at a low dose and slowly increase your dose. Follow your medical practitioner's instructions very carefully.

Just take this medication regularly in order to have the benefit that is most from it. To help you remember, take it at the time( that is same) every day. Do not increase your dosage or use this drug more often or for longer than recommended. Your condition shall not improve any faster, and your threat of side effects will increase.

It is critical to carry on taking this medicine also if you feel well. Do not stop taking this medication without consulting your doctor. Some conditions may be worse whenever this drug is abruptly stopped. Also, you might experience symptoms such as mood swings, headache, tiredness, and sleep change. To prevent these symptoms while you are stopping treatment with this drug, your doctor may reduce your dose gradually. Consult your pharmacist or doctor for lots more details. Report any new or worsening symptoms right away.

This medication may not away work right. You may see some benefit within a week. However, it may take up to 4 weeks before you feel the full effect.

Tell your physician if your condition persists or worsens (such as your feelings of sadness worsen, or you have thoughts of suicide).

Part Effects

See also Warning section.

Drowsiness, dizziness, dry mouth, blurred eyesight, constipation, fat gain, or trouble urinating may occur. If any of these effects persist or worsen, notify your pharmacist or doctor promptly.

To reduce the danger of dizziness and lightheadedness, get up slowly when rising from a sitting or position that is lying.

To relieve mouth that is dry suck on (sugarless) hard candy or ice potato chips, chew (sugarless) gum, drink water, or utilize a saliva substitute.

To prevent constipation, keep a diet adequate in fiber, beverage plenty of water, and exercise. In the event that you become constipated while by using this medication, consult your pharmacist for help in selecting a laxative.

Keep in mind that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.

Tell your doctor right away if any of the rare but adverse that is serious occur: easy bruising/bleeding, persistent heartburn, shaking, mask-like facial expressions, muscle spasms, severe stomach/abdominal discomfort, decreased sexual ability/desire, enlarged/painful breasts.

Get medical help right away if you have any very serious adverse effects, including: black stools, vomit that seems like coffee grounds, serious dizziness, fainting, seizures, attention pain/swelling/redness, eyesight changes (such as seeing rainbows around lights at night).

This medication may rarely cause a very serious condition called neuroleptic malignant syndrome (NMS). Get medical help right away when you have any of the following signs: temperature, muscle tissue stiffness, severe confusion, perspiring, fast/irregular heartbeat.

A very serious reaction that is allergic this drug is rare. However, seek immediate medical attention if you notice any outward symptoms of a significant allergic attack, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.

This will be perhaps not a complete list of possible adverse effects. If you notice other effects not listed above, contact your doctor or pharmacist.

In the US -

Phone your doctor for medical advice about adverse impacts. You may report effects that are side FDA at 1-800-FDA-1088 or at

In Canada - Call your medical practitioner for medical advice about side effects. You may report effects that are side Health Canada at 1-866-234-2345.


See also Warning section.

Before taking amitriptyline, tell your medical practitioner or pharmacist in the event that you have any other allergies if you are allergic to it, or to other tricyclic antidepressants (such as nortriptyline), or. This product may contain ingredients that are inactive which could cause allergies or other issues. Talk to your pharmacist for more details.

Before applying this medication, tell your medical practitioner or pharmacist your medical history, especially of: bleeding problems, breathing problems, liver problems, recent heart assault, problems urinating (such as because of enlarged prostate), overactive thyroid (hyperthyroidism), individual or genealogy and family history of glaucoma (angle-closure type), personal or genealogy and family history of mental/mood conditions (such as manic depression, psychosis), household history of suicide, seizures, conditions that may increase your risk of seizures (such as other brain infection, alcohol withdrawal).

Amitriptyline may cause a disorder that affects the center rhythm (QT prolongation). QT prolongation can hardly ever cause serious (rarely fatal) fast/irregular heartbeat and other symptoms (such as severe dizziness, fainting) that require medical attention immediately.

The risk of QT prolongation might be increased when you have particular medical conditions or are taking other drugs that may cause QT prolongation. Before utilizing amitriptyline, tell your doctor or pharmacist of all drugs you take and in the event that you have actually any of the following conditions: certain heart problems (heart failure, slow heartbeat, QT prolongation within the EKG), family history of certain heart disease (QT prolongation in the EKG, unexpected cardiac death).

Low degrees of potassium or magnesium in the blood may increase your risk also of QT prolongation. This risk may increase if you use certain drugs (such as diuretics/"water pills") or if you have conditions such as severe sweating, diarrhea, or vomiting. Talk to your doctor about utilizing amitriptyline properly.

This drug may make you drowsy or dizzy or cause blurred vision. Do not drive, use machinery, or do any activity that requires alertness or clear vision you can perform such activities safely until you are sure. Avoid alcoholic beverages.

Before having surgery, tell your doctor or dental practitioner about all the products you use (including prescription drugs, nonprescription drugs, and herbal products).

This medication may make you more sensitive to the sun. Avoid prolonged sun exposure, tanning booths, and sunlamps. Use a sunscreen and wear protective clothing when outside.

If you have diabetes, this drug may make it harder to control your blood sugar levels. Monitor your blood sugar levels regularly and tell your doctor of the results. Your doctor may need to adjust your diabetes medicine, exercise program, or diet.

Older adults may be more responsive to the side-effects of this drug, specially dry mouth, dizziness, drowsiness, confusion, constipation, difficulty urinating, and QT prolongation (see above). Dizziness, drowsiness, and confusion can boost the danger of falling.

During pregnancy, this medication should be used only when demonstrably required. Discuss the potential risks and benefits with your physician.

Since untreated mental/mood issues (such as depression, anxiety, panic disorder) can be a serious condition, do not stop using this medication unless directed by your doctor. If you are planning pregnancy, become pregnant, or think you may be pregnant, immediately discuss with your doctor the benefits and risks of using this medication during pregnancy.

This medication passes into breast milk and the result on a nursing infant is unknown. Consult with your doctor before breast-feeding.

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