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Uses

INDICATIONS

Imuran can be used to avoid rejection of your transplanted kidney. It is one of the band of medicines generally known as immunosuppressive agents. Azathioprine will lower your body's natural immunity in patients who receive transplants to avoid rejection with the new kidney. It is also accustomed to relieve joint pain and swelling for patients with rheumatoid arthritis symptoms.

INSTRUCTIONS

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Use this medicine just as directed by your doctor. Do not take much more of it, or a smaller amount of it, than your physician ordered. Taking an excessive amount of may increase the chance of unwanted effects, and taking weak hands won't help your problem.

This drugs are sometimes given together with other medicines. If you are utilizing several medicines together, make sure you discover how to drive them in daytime. Ask a medical expert to assist you plan a way to make sure to take your medicines with the right times.

Do not stop taking this medicine without first checking with your medical professional.

Imuran sometimes causes nausea / vomiting. Taking this medicine after meals or at night may lessen stomach upset. Talk to your physician when you have questions or continue to have difficulty with nausea or vomiting.

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If you miss a dose with this medicine, get it immediately. However, when it is almost time for your upcoming dose, skip the missed dose and get back on your normal dosing schedule. Do not double doses.

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DOSAGE

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The dose on this medicine will change for different patients. Follow your medical professional's orders or perhaps the directions on the label. The following information includes just the average doses with this medicine. If your dose differs, don't change it unless your medical professional lets you know to do this.

The quantity of medicine which you take depends around the strength with the medicine. Also, the quantity of doses you are taking on a daily basis, time allowed between doses, and the time period you are taking the medicine depend for the medical problem that you can are choosing the medicine.
For oral dosage form (tablets):
For kidney transplant rejection:

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For arthritis rheumatoid: 

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STORAGE 

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Store the medicine in a closed container at room temperature, from heat, moisture, and direct light. Keep from freezing.
Keep out in the reach of youngsters.
Do not keep outdated medicine or medicine will no longer needed.
Ask your healthcare professional how you should dispose of any medicine you tend not to use.

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Side Effects

Along featuring its needed effects, medicine might cause some unwanted effects. Although not all of these unwanted effects may occur, should they occur they may need medical assistance.

Check with your physician immediately if any from the following unwanted side effects occur:


More common

Rare 

Incidence not known

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Some unwanted side effects may occur very often usually do not need medical attention. These negative effects might have to go away during treatment because your body adjusts towards the medicine. Also, your overall health care professional just might let you know about ways to stop or reduce many of these negative effects. Check along with your health care professional if any with the following side effects continue or are bothersome or when you have any queries about them:
More common
Nausea or vomiting (mild)
swollen joints
Incidence not known
Hair loss or thinning from the hair

Other unwanted effects not listed might also happen in some patients. If you notice some other effects, check along with your health care professional.

Call your doctor for medical health advice about side effects.

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Precautions

If you may be using this medicine for a long period, it is vital that your physician check you at regular visits for virtually any problems or unwanted effects which might be caused by this medicine. Blood tests may be needed to evaluate for unwanted side effects.

Using this medicine if you are pregnant can harm your baby. Use an effective kind of birth control to help keep from getting pregnant. If you think you might have conceive with all the this medicine, tell a medical expert without delay.

Do not make use of this medicine should you be also taking mercaptopurine (Purinethol®). Using these medicines together could cause serious unwanted side effects.

If you are employing azathioprine for arthritis, make sure your doctor knows should you received chlorambucil (Leukeran®), cyclophosphamide (Cytoxan®, Neosar®), or melphalan (Alkeran®) to take care of your arthritis inside past. Using azathioprine after these medicines may enhance your risk for unwanted effects. Talk to your doctor in case you have questions regarding this.

This medicine may raise your risk of getting some types of cancer, especially of the skin, lymph system (lymphoma), or blood (leukemia). Talk to your doctor when you have concerns relating to this risk.

Use sunscreen or sunblock lotions with a sun-protection factor (SPF) of at least 15 often when you're outdoors. Wear protective clothing and hats, and turn into beyond sunlight involving the hours of 10 a.m. and 3 p.m. Avoid sunlamps and tanning beds.

While you are receiving treatment with azathioprine, and when you stop treatment by using it, don't have any immunizations (vaccines) without a medical expert's approval. Azathioprine may lessen your body's resistance and also the vaccine may not work as well or you'll have the infection the vaccine is meant to prevent. In addition, you ought not be around other persons residing in all your family members who receive live virus vaccines because there is a chance they might pass the herpes simplex virus on you. Some examples of live vaccines include measles, mumps, influenza (nasal flu vaccine), poliovirus (oral form), rotavirus, and rubella. Do not get near to them and tend not to stay within the same room with these for days on end. If you've got questions about this, talk to your medical professional.

Azathioprine can temporarily lower the quantity of white blood cells within your blood, enhancing the probability of getting an infection. It can also lower the amount of platelets, which can be required for proper blood clotting. If this occurs, there are particular precautions you'll be able to take, especially when your blood count is low, to reduce the risk of infection or bleeding:

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Check with your doctor immediately when you have multiple of those symptoms while you are employing this medicine: severe queasiness; diarrhea; fever; rash; an over-all a feeling of discomfort or illness; muscle or joint; lightheadedness or dizziness; or unusual tiredness or weakness. These could be symptoms of the serious reaction towards the medicine inside your bowel (intestine).

Do not take other medicines unless they have been discussed with your doctor. This includes prescription or nonprescription (over-the-counter [OTC]) medicines and herbal or nutritional vitamin supplements.

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