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Uses

INDICATIONS

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Keppra is used to deal with partial onset seizures in grown-ups and kids that are at least 30 days old.
It can be used to deal with tonic-clonic seizures in adults and kids who are at least 6 years of age, and myoclonic seizures in older adults and children who're at least 12 yrs . old.

INSTRUCTIONS

Take Keppra exactly as prescribed by your doctor. Do not take in larger or smaller amounts or for longer than recommended. Follow the directions in your prescription label.

Your doctor may occasionally make positive changes to dose to ensure that you receive the best results.

Keppra is generally taken twice each day. Take the medicine at the same time every day. You may take Keppra with or without food.

Measure liquid medicine with a special dose-measuring spoon or medicine cup, not using a regular table spoon. If you do not use a dose-measuring device, ask your pharmacist for starters.
Do not crush, chew, or break a controlled release, delayed-release, or extended-release tablet. Swallow it whole. Breaking the pill might cause a lot of drug to be sold in the past.

Use Keppra regularly to get the most benefit. Get your prescription refilled before you run out of drugs completely.

Do not stop using Keppra without first speaking with a medical expert, even if you feel great. You may have increased seizures should you stop by using this medicine suddenly. You might need to use less before you stop the medication completely.

Seizures will often be treated having a combination of different drugs. Use all medications as directed by your doctor. Read the medication guide or patient instructions provided with each medication. Do not alter your doses or medication schedule without a medical expert's advice. .

Wear a medical alert tag or carry an ID card on the grounds that you are taking Keppra. Any health care bills provider who treats you should know that you take seizure medication.

To be sure Keppra isn't causing harmful effects, your kidney function might need to be tested. Visit your medical professional regularly.

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If you missed a dose - take the missed dose as soon as you remember. Skip the missed dose if it's almost time for your upcoming scheduled dose. Do not take extra medicine to generate inside the missed dose.

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DOSAGE

Important Administration Instructions

Keppra emerged orally with or without food. The Keppra dosing regimen is determined by the indication, generation, dosage form (tablets or oral solution), and renal function.

Prescribe the oral solution for pediatric patients with weight ≤ 20 kg. Prescribe the oral solution or tablets for pediatric patients with weight above 20 kg.

When with all the oral solution in pediatric patients, dosing is weight-based (mg per kg) using a calibrated measuring device (not really a household teaspoon or tablespoon).
Keppra tablets must be swallowed whole. Keppra tablets should not be chewed or crushed.

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Pediatric Patients

Treatment needs to be initiated having a daily dose of 14 mg/kg into two divided doses (7 mg/kg two tmes a day). The daily dose ought to be increased every 2 weeks by increments of 14 mg/kg towards the recommended daily dose of 42 mg/kg (21 mg/kg twice a day). In the clinical study, the mean daily dose was 35 mg/kg on this age bracket. The effectiveness of lower doses has not been studied.

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Treatment should be initiated having a daily dose of 20 mg/kg by 50 percent divided doses (10 mg/kg twice a day). The daily dose must be increased in 2 weeks by an increment of 20 mg/kg to the recommended daily dose of 50 mg/kg (25 mg/kg two times a day). If a patient cannot tolerate a day-to-day dose of 50 mg/kg, the daily dose could be reduced. In the clinical trial, the mean daily dose was 47 mg/kg within this population.

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Treatment ought to be initiated using a daily dose of 20 mg/kg by 50 percent divided doses (10 mg/kg two times a day). The daily dose ought to be increased every two weeks by increments of 20 mg/kg to the recommended daily dose of 60 mg/kg (30 mg/kg twice daily). If a patient cannot tolerate a day-to-day dose of 60 mg/kg, the daily dose might be reduced. In the clinical efficacy trial, the mean daily dose was 44 mg/kg. The maximum daily dose was 3000 mg/day.

For Keppra tablet dosing in pediatric patients weighing 20 to 40 kg, treatment needs to be initiated having a daily dose of 500 mg given as twice a day dosing (250 mg two times a day). The daily dose must be increased every fourteen days by increments of 500 mg with a maximum recommended daily dose of 1500 mg (750 mg twice daily).

For Keppra tablet dosing in pediatric patients weighing a lot more than 40 kg, treatment needs to be initiated using a daily dose of 1000 mg/day given as two tmes a day dosing (500 mg twice daily). The daily dose should be increased every fourteen days by increments of 1000 mg/day with a maximum recommended daily dose of 3000 mg (1500 mg two tmes a day).

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Partial Onset Seizures
Adults 16 Years And Older

In clinical trials, daily doses of 1000 mg, 2000 mg, and 3000 mg, given as twice-daily dosing were been shown to be effective. Although in some studies there was a tendency toward greater response with higher dose [see Clinical Studies], a frequent surge in response to comprehend dose hasn't been shown.

Treatment must be initiated having a daily dose of 1000 mg/day, given as twice-daily dosing (500 mg two times a day). Additional dosing increments could possibly be given (1000 mg/day additional every 14 days) to a maximum recommended daily dose of 3000 mg. Doses more than 3000 mg/day are actually found in open-label studies for periods of six months and longer. There is no evidence that doses greater than 3000 mg/day confer additional benefit.

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Myoclonic Seizures In Patients 12 Years of Age and Older With Juvenile Myoclonic Epilepsy
Treatment must be initiated having a dose of 1000 mg/day, given as twice-daily dosing (500 mg twice a day). Dosage ought to be increased by 1000 mg/day every two weeks on the recommended daily dose of 3000 mg. The effectiveness of doses under 3000 mg/day is not studied.

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Primary Generalized Tonic-Clonic Seizures
Adults 16 Years And Older
Treatment needs to be initiated having a dose of 1000 mg/day, given as twice-daily dosing (500 mg twice daily). Dosage needs to be increased by 1000 mg/day every two weeks for the recommended daily dose of 3000 mg. The effectiveness of doses under 3000 mg/day is not adequately studied.

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Pediatric Patients Ages 6 To < 16 Years
Treatment needs to be initiated having a daily dose of 20 mg/kg by 50 % divided doses (10 mg/kg two tmes a day). The daily dose must be increased every 14 days by increments of 20 mg/kg towards the recommended daily dose of 60 mg/kg (30 mg/kg two tmes a day). The effectiveness of doses less than 60 mg/kg/day hasn't been adequately studied. Patients with bodyweight ≤ 20 kg should be dosed with oral solution. Patients with weight above 20 kg may be dosed with either tablets or oral solution. Only whole tablets should be administered.

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Adult Patients With Impaired Renal Function
Keppra dosing has to be individualized according for the patient's renal function status.

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STORAGE

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Store Keppra at room temperature far from moisture, heat, and light.

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Side Effects

Get emergency medical help in case you have any of these warning signs of a hypersensitive reaction to Keppra: hives; difficult breathing; swelling of the face, lips, tongue, or throat.

Report any new or worsening symptoms to your medical professional, including: mood or behavior changes, depression, anxiety, or should you feel agitated, hostile, irritable, hyperactive (mentally or physically), or have thoughts about suicide or hurting yourself.

Call your doctor immediately in case you have a very serious side-effect for example:

Less serious Keppra side effects can include:

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This just isn't a complete set of side effects and others may occur. Tell your medical professional about any unusual or bothersome side effect.

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Precautions

You should not use Keppra in the event you are allergic to levetiracetam.

To be sure to can safely take Keppra, tell your physician in the event you have kidney disease or blood pressure.

You might have thoughts about suicide while taking this medicine. Tell your doctor in case you have symptoms of depression or suicidal thoughts during the first weeks of treatment, or when your dose is changed.

Your family or other caregivers should also be attentive to changes with your mood or symptoms. Your doctor will likely need to check you at regular visits.

FDA pregnancy category C. It just isn't known whether Keppra will harm an developing fetus, but having a seizure during pregnancy could harm the mother along with the baby. Tell your physician in case you are pregnant or intend to get pregnant while using this medication. Do not start or stop taking Keppra when pregnant without your physician's advice. Seizure control is critical during pregnancy. The benefit of preventing seizures may outweigh any risks presented by taking Keppra. Follow a medical expert's instructions about taking Keppra while you're pregnant. Levetiracetam can pass into breast milk and could harm a nursing baby. You should not breast-feed when you are using Keppra. Do not give prescription drugs with a child devoid of the advice of a doctor. Your child's dose needs are based on age and weight. The child should remain beneath the care of your doctor while applying this medicine.

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Do not stop using Keppra without first conversing with your physician, even though you feel awesome. You could possibly have increased seizures if you stop using Keppra suddenly. You should use less and less when you stop the medication completely.

You could possibly have thoughts about suicide while taking Keppra. Your doctor will likely need to check you at regular visits. Do not miss any scheduled appointments.

Report any new or worsening symptoms to a medical expert, such as: mood or behavior changes, depression, anxiety, or in case you feel agitated, hostile, irritable, hyperactive (mentally or physically), or have thoughts about suicide or hurting yourself.

Wear a medical alert tag or carry an ID card proclaiming that you are taking Keppra. Any medical care provider who treats you need to know that you're taking seizure medication.

Keppra may impair your thinking or reactions. Be careful in case you drive or do just about anything that will need you to definitely be alert. Tell your physician in the event you are pregnant or prefer to become pregnant while applying this medication. Do not start or stop taking Keppra when pregnant without a medical expert's advice. Having a seizure during pregnancy could harm both mother as well as the baby. Seizure control is essential during pregnancy and also the advantages of preventing seizures may outweigh any risks presented by using Keppra.

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Avoid drinking alcohol. It can increase a few of the unwanted side effects of Keppra and might could also increase potential risk of seizures. This medication may impair your opinions or reactions. Be careful if you drive or do anything that requires you to definitely be alert.

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