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Uses

INDICATIONS

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Keppra can be used to help remedy partial onset seizures in grown-ups and children who are no less than 30 days old.
It can be used to treat tonic-clonic seizures in adults and youngsters who're at the very least 6 yrs . old, and myoclonic seizures in grown-ups and youngsters who will be at the very least 12 years.

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INSTRUCTIONS

Take Keppra the same manner prescribed because of your doctor. Do not take in larger or smaller amounts and over recommended. Follow the directions on your own prescription label.

Your doctor may occasionally alter your dose to ensure that you get the best results.

Keppra is often taken twice every day. Take the medicine concurrently daily. You may take Keppra with or without food.

Measure liquid medicine with a special dose-measuring spoon or medicine cup, not using a regular table spoon. If you do not have a dose-measuring device, ask your pharmacist for starters.
Do not crush, chew, or break a controlled release, delayed-release, or extended-release tablet. Swallow it whole. Breaking the pill might cause too much of the drug to be removed at once.

Use Keppra regularly to obtain the most benefit. Get your prescription refilled before you run out of medicine completely.

Do not stop using Keppra without first actually talking to a medical expert, in case you feel awesome. You might have increased seizures should you stop by using this medicine suddenly. You may need to use much less before you stop the medication completely.

Seizures will often be treated having a combination of different drugs. Use all medications as directed through your doctor. Read the medication guide or patient instructions furnished with each medication. Do not alter your doses or medication schedule without your doctor's advice. .

Wear a medical alert tag or carry an ID card proclaiming that you are taking Keppra. Any health care provider who treats you need to understand that you're taking seizure medication.

To make sure Keppra just isn't causing harmful effects, your kidney function should be tested. Visit your medical professional regularly.

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If you missed a dose - consider the missed dose as soon as you remember. Skip the missed dose if it's almost time for your upcoming scheduled dose. Do not take extra medicine to generate up the missed dose.

DOSAGE

Important Administration Instructions

Keppra is given orally with or without food. The Keppra dosing regimen depends on the indication, age bracket, dosage form (tablets or oral solution), and renal function.

Prescribe the oral solution for pediatric patients with body weight ≤ 20 kg. Prescribe the oral solution or tablets for pediatric patients with weight above 20 kg.

When while using the oral solution in pediatric patients, dosing is weight-based (mg per kg) using a calibrated measuring device (not just a household teaspoon or tablespoon).
Keppra tablets needs to be swallowed whole. Keppra tablets really should not be chewed or crushed.

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Pediatric Patients

Treatment ought to be initiated having a daily dose of 14 mg/kg in 2 divided doses (7 mg/kg two tmes a day). The daily dose must be increased every 14 days by increments of 14 mg/kg for the recommended daily dose of 42 mg/kg (21 mg/kg two tmes a day). In the clinical trial, the mean daily dose was 35 mg/kg on this age bracket. The effectiveness of lower doses has not been studied.

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Treatment ought to be initiated having a daily dose of 20 mg/kg by 50 percent divided doses (10 mg/kg two times a day). The daily dose ought to be increased in 2 weeks by an increment of 20 mg/kg on the recommended daily dose of 50 mg/kg (25 mg/kg twice daily). If a patient cannot tolerate a day-to-day dose of 50 mg/kg, the daily dose might be reduced. In the medical trial, the mean daily dose was 47 mg/kg in this generation.

Treatment should be initiated having a daily dose of 20 mg/kg into two divided doses (10 mg/kg twice daily). The daily dose ought to be increased every 2 weeks by increments of 20 mg/kg for the recommended daily dose of 60 mg/kg (30 mg/kg two tmes a day). If a patient cannot tolerate a daily dose of 60 mg/kg, the daily dose might be reduced. In the clinical efficacy trial, the mean daily dose was 44 mg/kg. The maximum daily dose was 3000 mg/day.

For Keppra tablet dosing in pediatric patients weighing 20 to 40 kg, treatment should be initiated having a daily dose of 500 mg given as twice a day dosing (250 mg twice a day). The daily dose should be increased every two weeks by increments of 500 mg with a maximum recommended daily dose of 1500 mg (750 mg twice a day).

For Keppra tablet dosing in pediatric patients weighing more than 40 kg, treatment must be initiated which has a daily dose of 1000 mg/day given as two tmes a day dosing (500 mg twice daily). The daily dose must be increased every 14 days by increments of 1000 mg/day to some maximum recommended daily dose of 3000 mg (1500 mg twice daily).

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Partial Onset Seizures
Adults 16 Years And Older

In many studies, daily doses of 1000 mg, 2000 mg, and 3000 mg, given as twice-daily dosing were proved to be effective. Although in a few studies there were a propensity toward greater response with higher dose [see Clinical Studies], a consistent rise in response with additional dose has not been shown.

Treatment must be initiated using a daily dose of 1000 mg/day, given as twice-daily dosing (500 mg twice a day). Additional dosing increments could be given (1000 mg/day additional every two weeks) to a maximum recommended daily dose of 3000 mg. Doses greater than 3000 mg/day have been utilized in open-label studies for periods of a few months and longer. There is no evidence that doses in excess of 3000 mg/day confer additional benefit.

Myoclonic Seizures In Patients 12 Years of Age and Older With Juvenile Myoclonic Epilepsy
Treatment ought to be initiated using a dose of 1000 mg/day, given as twice-daily dosing (500 mg twice a day). Dosage ought to be increased by 1000 mg/day every fourteen days towards the recommended daily dose of 3000 mg. The effectiveness of doses lower than 3000 mg/day hasn't been studied.


Primary Generalized Tonic-Clonic Seizures
Adults 16 Years And Older
Treatment should be initiated having a dose of 1000 mg/day, given as twice-daily dosing (500 mg two tmes a day). Dosage must be increased by 1000 mg/day every fourteen days to the recommended daily dose of 3000 mg. The effectiveness of doses under 3000 mg/day hasn't been adequately studied.

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Pediatric Patients Ages 6 To < 16 Years
Treatment needs to be initiated having a daily dose of 20 mg/kg by 50 percent divided doses (10 mg/kg two times a day). The daily dose should be increased every fourteen days by increments of 20 mg/kg to the recommended daily dose of 60 mg/kg (30 mg/kg twice a day). The effectiveness of doses under 60 mg/kg/day will not be adequately studied. Patients with weight ≤ 20 kg ought to be dosed with oral solution. Patients with body mass above 20 kg might be dosed with either tablets or oral solution. Only whole tablets must be administered.


Adult Patients With Impaired Renal Function
Keppra dosing has to be individualized according towards the patient's renal function status.

STORAGE

Store Keppra at room temperature from moisture, heat, and light-weight.

Side Effects

Get emergency medical help if you have some of these signs of an allergic reaction to Keppra: hives; difficult breathing; swelling of one's face, lips, tongue, or throat.

Report any new or worsening symptoms to a medical expert, including: mood or behavior changes, depression, anxiety, or in the event you feel agitated, hostile, irritable, hyperactive (mentally or physically), or have thoughts about suicide or hurting yourself.

Call your medical professional immediately in case you have a very serious side-effect including:

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Less serious Keppra unwanted side effects might include:

This is just not a complete report on negative effects yet others may occur. Tell your physician about any unusual or bothersome complication.

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Precautions

You should avoid using Keppra should you are allergic to levetiracetam.

To ensure you can safely take Keppra, tell your doctor should you have kidney disease or hypertension.

You could possibly have thoughts about suicide while using this medicine. Tell your medical professional should you have the signs of depression or suicidal thoughts in the first several weeks of treatment, or whenever your dose is changed.

Your family or any other caregivers should also be tuned in to changes in your mood or symptoms. Your doctor will have to check you at regular visits.

FDA pregnancy category C. It isn't known whether Keppra will harm an baby, but developing a seizure when pregnant could harm both mother as well as the baby. Tell your medical professional in case you are pregnant or intend to get pregnant while employing this medication. Do not start or stop taking Keppra when pregnant without your doctor's advice. Seizure control is essential while pregnant. The benefit of preventing seizures may outweigh any risks posed by taking Keppra. Follow your medical professional's instructions about taking Keppra if you are pregnant. Levetiracetam can pass into breast milk and might harm a nursing baby. You should not breast-feed while you're using Keppra. Do not give this medication to a child without the advice of an doctor. Your child's dose needs are based on age and weight. The child should remain within the care of a doctor while using this medicine.

Do not stop using Keppra without first speaking with your medical professional, even though you feel great. You could have increased seizures in case you stop using Keppra suddenly. You ought to use less prior to deciding to stop the medication completely.

You could have thoughts about suicide while taking Keppra. Your doctor will need to check you at regular visits. Do not miss any scheduled appointments.

Report any new or worsening symptoms to your doctor, for example: mood or behavior changes, depression, anxiety, or in the event you feel agitated, hostile, irritable, hyperactive (mentally or physically), or have thoughts about suicide or hurting yourself.

Wear a medical alert tag or carry an ID card stating that you adopt Keppra. Any health care bills provider who treats you have to know that you are taking seizure medication.

Keppra may impair your notions or reactions. Be careful in the event you drive or a single thing that will require you to definitely be alert. Tell your medical professional in the event you are pregnant or intend to become pregnant while by using this medication. Do not start or stop taking Keppra when pregnant without your medical professional's advice. Having a seizure in pregnancy could harm the mother and also the baby. Seizure control is essential in pregnancy as well as the advantages of preventing seizures may outweigh any risks posed by using Keppra.

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Avoid drinking alcohol. It can increase a number of the negative effects of Keppra and may even could also increase potential risk of seizures. This medication may impair your notions or reactions. Be careful if you drive or do just about anything that requires you to definitely be alert.

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