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Uses

INDICATIONS

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Meldonium treats heart ischemia and its consequencesis.  It is found in treating brain circulation disorders. Meldonium is assumed to improve Mental Processes (Memory, Learning, Focus, Concentration, Processing of Information) and reduces Fatigue, Increases Motivation & Alertness. Meldonium was made to boost Athletic Training & Competitive Performance too as microcirculation & Oxygen Delivery.

Due to its unique mechanism of action Mildronate, with respect to the prescribed dose, is popular for the treatment of different heart and vascular diseases, at the same time as for the improvement at work capacity of healthy people at both mental and physical overloads and during rehabilitation period.

INSTRUCTIONS

Applied internally.

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• Intellectual and physical stress (including in athletes). Adults – 1 g each day
divided into two 500mg doses. Course of treatment is 10-14 days. If necessary, the procedure is repeated in 2-3 weeks.

• Athletes should take 500 mg – 1 g twice a day before training. Duration of
treatment during preparatory period is 2-3 weeks, throughout competition – 10-14 days.

• Cardiovascular disease. As part of combined therapy: 500 mg -1 g (1-2 tablets) every day, utilizing the whole dose in the past or dividing for two takings. Course of treatment is 4-6 weeks.

• Cardialgia contrary to the background of dyshormonal myocardiodystrophy – 500 mg each day. Course of treatment is 12 days.

• Disturbed cerebral circulation. In procedure after reduction of acute disorders: 500 mg – 1 g every day, utilizing the whole dose in the past or dividing it for 2 takings. In case of chronic disorders: 500 mg every day. General procedure is 4-6 weeks. Recurrent courses (usually 2-3 times 12 months) could possibly be taken after consulting a doctor.

• Diseases of peripheral arteries. 500 mg twice a day.

• Abstinence syndrome in case there is chronic alcoholism. 500 mg 4 times every day. Course of treatment is 7-10 days.

• Maximum daily dose is 2000 mg.

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Please talk to your physician before applying this or some other vitamins and minerals or medications.

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DOSAGE

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Please consult your doctor in connection with required dosage.

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Overdosage
There isn't data of cases of Meldonium overdosage. The drug is low-toxic.

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STORAGE 

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Keep from sunlight.
Keep locked and faraway from children.
Store in dry place at room temperature.
Do not exceed storage temperature higher than 25 C

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Side Effects

Rarely - hypersensitive reactions (redness, rash, itching, oedema), also as dyspepsia, tachycardia, excitement, changes of arterial pressure.

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Precautions

Contraindications:

Hypersensitivity, increased intracranial pressure (in violation from the venous outflow, intracranial tumors).

Restrictions:

Pregnancy, lactation, children under 18 (capsule, injectable solution) or 12 years (syrup), since safety and efficacy have not been determined.

Pregnancy and breast-feeding:

Not recommended in pregnancy (safety weren't proven). At the time of treatment should stop breastfeeding (known whether the breast milk gets).

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Interaction along with other drugs and also other forms of interaction

The drug could possibly be along with antianginal agents, anticoagulants and antiaggregants, antiarrhythmic drugs, diuretics, and bronchial spasmolytics. It intensifies the action of coronary vasodilating drugs, some hypotensive agents, and cardiac glycosides. Taking into consideration the possible growth and development of mild tachycardia and arterial hypotension, care should be taken when combining the drug with nitroglycerin, nifediphine, alpha-adrenoceptor blockers, hypotensive agents and peripheral vasodilators.

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