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Mestinon (Pyridostigmine) affects chemicals within the body that are mixed up in the communication between nerve impulses and muscle movement.

Pyridostigmine is employed to help remedy the signs and symptoms of myasthenia gravis. It is also employed in military personnel who had been subjected to nerve gas.

Pyridostigmine could also be used for purposes unpublished with this medication guide.

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Take exactly as prescribed by your doctor. Do not take in larger or smaller amounts and more than recommended. Follow the directions on your prescription label.
Take this medicine with food or milk when it upsets your stomach. Do not crush, chew, or break an extended-release tablet. Swallow it whole. Breaking or opening the pill might cause a lot of drug to be sold at once.

Measure liquid medicine using a special dose measuring spoon or medicine cup, not with a regular table spoon. If you do not have a dose measuring device, ask the pharmacist for one.

The amount and timing of the prescription medication is very important to the success of your respective treatment. Carefully follow your medical professional's instructions about how much medicine to take so when to take it.

Your doctor may occasionally improve your dose to ensure that you acquire the best results. You may be asked to keep a daily record of if you took each dose and how long the end results lasted. This will help your medical professional determine if your dose has to be adjusted.
If you need surgery, tell the surgeon beforehand that you're using pyridostigmine. You may need to stop while using medicine to get a limited time. Store at room temperature far from moisture and also heat.


Take the medicine as prescribed because of your doctor.

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Keep the tablets in their original container, combined with canister of moisture-absorbing preservative that is included with this medicine.

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Active ingredient: Pyridostigmine

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Side Effects

Get emergency medical help when you have any of these warning signs of a hypersensitive reaction: hives; difficulty breathing; swelling of one's face, lips, tongue, or throat. Stop using pyridostigmine and call your physician immediately for those who have any of these serious side effects:

extreme muscle weakness, muscle twicthing;

slurred speech, vision problems;

severe vomiting or diarrhea;

cough with mucus;

confusion, anxiety, anxiety attacks;

seizure (convulsions); or

worsening or no improvement inside your signs of myasthenia gravis.

Less serious unwanted side effects can sometimes include:

cold sweat, pale skin;

urinating more than usual;

watery eyes;

mild nausea, vomiting, or upset stomach;

warmth or tingly feeling; or

mild rash or itching.

This isn't a complete listing of unwanted effects while others may occur. Call your medical professional for health advice about negative effects.

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You should avoid using pyridostigmine if you are allergic to it, or if you have a very bladder or bowel obstruction.

To be sure you can safely take pyridostigmine, tell your physician in case you have some of these other conditions:


kidney disease;

an ulcer and other serious stomach disorder;

high blood pressure levels, coronary disease;

overactive thyroid; or

a reputation seizures.

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It is just not known whether pyridostigmine will harm an baby. Tell a medical expert if you're pregnant or intend to get pregnant when using medicines. It just isn't known whether pyridostigmine passes into breast milk or whether or not this could harm a nursing baby. Do not use this medication without telling your doctor should you be breast-feeding a child.

Drugs interaction 

Tell your physician about all the medicines you utilize, especially:

atropine (Atreza, Sal-Tropine);

belladonna (Donnatal, among others);

benztropine (Cogentin);

clidinium (Quarzan);

clozapine (Clozaril, FazaClo);

dimenhydrinate (Dramamine);

methscopolamine (Pamine), scopolamine (Transderm Scop);

glycopyrrolate (Robinul);

mepenzolate (Cantil);

bladder or urinary medications such as darifenacin (Enablex), flavoxate (Urispas), oxybutynin (Ditropan, Oxytrol), tolterodine (Detrol), or solifenacin (Vesicare);

bronchodilators including ipratropium (Atrovent) or tiotropium (Spiriva);

cold medicine, allergy medicine, or sleeping pills that have an antihistamine for example diphenhydramine (Tylenol PM) or doxylamine (Unisom);

heart rhythm medication for example quinidine (Quin-G), procainamide (Procan, Pronestyl), disopyramide (Norpace), flecaininde (Tambocor), mexiletine (Mexitil), propafenone, (Rythmol), while others;

irritable bowel medications like dicyclomine (Bentyl), hyoscyamine (Hyomax), or propantheline (Pro Banthine);

medicine to treat Alzheimer's dementia, including donepezil (Aricept), rivastigmine (Exelon), or tacrine (Cognex); or

a steroid for example betamethasone (Celestone) or dexamethasone (Cortastat, Dexasone, Solurex, DexPak).

This list isn't complete and also other drugs may connect to pyridostigmine. Tell your medical professional about all medications you employ. This includes prescription, over-the-counter, vitamin, and herbal products. Do not begin a new medication without telling your doctor.

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