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Micronase (Glyburide) is surely an oral diabetes medicine that assists control blood sugar levels.

Glyburide is employed to treat type 2 diabetes.

This medicine is not for treating type 1 diabetes.

Glyburide could also be used for other purposes unlisted on this medication guide.

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Take just as prescribed by your doctor. Do not take in larger or smaller amounts and for more than recommended. Follow the directions on your own prescription label. Your doctor may occasionally change your dose to make sure you acquire the best results.

Take glyburide along with your first meal through the day, unless your medical professional informs you otherwise.

Your blood sugar levels should be checked often, and you'll need other blood tests at your doctor's office. Visit your doctor regularly.
Know the signs and symptoms of low blood glucose (hypoglycemia) and ways to recognize them: headache, hunger, weakness, sweating, tremor, irritability, or trouble concentrating.

Always keep a method to obtain sugar for sale in case you have signs and symptoms of low blood glucose. Sugar sources include orange juice, glucose gel, candy, or milk. If you might have severe hypoglycemia and should not eat or drink, work with an injection of glucagon. Your doctor can provide you with a prescription to get a glucagon emergency injection kit and tell you how you can provide injection.

Also look for warning signs of blood sugar that is excessive (hyperglycemia). These symptoms include increased thirst, increased urination, hunger, dry mouth, fruity breath odor, drowsiness, dried-out skin, blurred vision, and fat loss.

Check your blood sugar levels carefully after a period of stress or illness, in case you travel, exercise more than usual, are drinking alcohol, or skip meals. These things may affect your blood sugar levels and your dose needs might also change.

Your doctor may wish you to stop taking glyburide for the limited time in the event you get sick, have a very fever or infection, or if you might have surgery or a medical emergency.
Ask your doctor the best way to adjust your glyburide dose if needed. Do not make positive changes to medication dose or schedule without your physician's advice.

If there are any modifications in the company, strength, or sort of glyburide you utilize, your dosage needs may change. Always check your refills to ensure that you have received the right brand and form of medicine prescribed through your doctor.


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Take as prescribed from your doctor.


Store at room temperature, protected from moisture, heat, and light-weight.


Active ingredient: Glyburide

Side Effects

Stop using glyburide and have emergency medical help if you have any of these indications of a hypersensitive reaction: hives; lack of breath; swelling of your face, lips, tongue, or throat. Stop taking medicines and call your physician at once if you've got any of these serious unwanted side effects:

nausea, stomach pain, low fever, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes);

pale skin, confusion or weakness;

easy bruising or bleeding, purple or red pinpoint spots through your skin; or

headache, trouble concentrating, memory problems, feeling unsteady, hallucinations, fainting, seizure, shallow breathing or breathing that stops.

Less serious negative effects can sometimes include:

mild nausea, heartburn, feeling full;

joint or muscle pain;

blurred vision; or

mild itching or skin rash.

This is not a complete set of unwanted side effects yet others may occur. Call your medical professional for medical advice about unwanted effects.

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You must avoid using prescription drugs if you are allergic to glyburide, or:

if you are receiving care with bosentan (Tracleer);

if you've type 1 diabetes; or

if you are in a state of diabetic ketoacidosis (call your physician for treatment with insulin).

To be sure you can safely take glyburide, tell your doctor if you might have some of these other conditions:

hemolytic anemia (deficiencies in red blood cells);

an enzyme deficiency called glucose-6-phosphate dehydrogenase deficiency (G6PD);

a nerve disorder affecting bodily functions;

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liver or kidney disease;

should you are allergic to sulfa drugs; or

if you've got been using insulin or taking chlorpropamide (Diabinese).

Certain oral diabetes medications may enhance your risk of serious cardiovascular disease. However, not handling your diabetes may damage your heart and also other organs. Talk to your medical professional regarding the risks and advantages of treating your diabetes with glyburide.

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FDA pregnancy category C. It is not known whether glyburide will harm an developing fetus. Similar diabetes medications have caused severe hypoglycemia in newborn babies whose mothers had used the medication near the duration of delivery. Tell your medical professional should you are pregnant or prefer to conceive when using medicines. It is not known whether glyburide passes into breast milk or if it might harm a nursing baby.

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Do not use prescription drugs without telling your medical professional in case you are breast-feeding a baby. Older adults may be prone to have low blood glucose levels while taking glyburide.


Important safety information:

You should not use medicines in case you are allergic to glyburide, if you are receiving treatment with bosentan (Tracleer), if you have type 1 diabetes, or if you are in a state of diabetic ketoacidosis (call your physician for treatment with insulin).

Before taking glyburide, tell a medical expert in the event you are allergic to sulfa drugs, if you might have been using insulin or chlorpropamide (Diabinese), or if you have hemolytic anemia (deficiencies in red blood cells), an enzyme deficiency (G6PD), a nerve disorder, liver disease, or kidney disease.

Take care to not let your blood glucose levels get too low. Low blood glucose (hypoglycemia) can occur in case you skip meals, exercise too long, consume alcohol, or are under stress. Symptoms include headache, hunger, weakness, sweating, tremor, irritability, or trouble concentrating. Carry hard candy or glucose tablets together with you in case you've got low blood glucose. Other sugar sources include orange juice and milk. Be sure your loved ones and buddies know how to assist you in an urgent situation.

Drug interactions

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Tell a medical expert about all the other medications you employ, especially:

a blood thinner such as warfarin (Coumadin, Jantoven);

cyclosporine (Gengraf, Neoral, Sandimmune);

disopyramide (Norpace);

fluconazole (Diflucan), ketoconazole (Nizoral);

fluoxetine (Prozac);

rifampin (Rifadin, Rimactane, Rifater);

an ACE inhibitor like enalapril (Vasotec), lisinopril (Prinivil, Zestril), ramipril (Altace), among others; or

an antibiotic like ciprofloxacin (Cipro), levofloxacin (Levaquin), yet others.

Using certain medicines makes it tougher for that you tell when you've low blood sugar. Tell your physician should you use any of these:

albuterol (Proventil, Ventolin);

clonidine (Catapres);

reserpine; or

beta-blockers including atenolol (Tenormin), carvedilol (Coreg), metoprolol (Lopressor, Toprol), propranolol (Inderal, InnoPran), yet others.

You may be more likely to have hyperglycemia (high blood glucose levels) in case you take glyburide with:


diuretics (water pills);

steroids (prednisone and others);

phenothiazines (Compazine while others);

thyroid medicine (Synthroid among others);

birth control pills along with other hormones;

heart or blood pressure levels medications (Cartia, Cardizem, Nifedical, Covera, Verelan, among others);

niacin (Advicor, Niaspan, Niacor, Simcor, Slo-Niacin, and others);

seizure medicines (Dilantin among others); and

diet pills or medicines to take care of asthma, colds or allergies.

You could possibly be prone to have hypoglycemia (low blood glucose levels) in case you take glyburide with:

clarithromycin (Biaxin);

exenatide (Byetta);

probenecid (Benemid);

heart or blood pressure medication (Accupril, Altace, Lotensin, Prinivil, Vasotec, Zestril, and others);

some nonsteroidal anti-inflammatory drugs (NSAIDs);

aspirin or other salicylates (including Pepto-Bismol);

sulfa drugs (Bactrim, Gantanol, Septra, yet others);

a monoamine oxidase inhibitor (MAOI); and

other oral diabetes medications, especially acarbose (Precose), metformin (Glucophage), miglitol (Glyset), pioglitazone (Actos), or rosiglitazone (Avandia).

These lists are certainly not complete and you'll find many other medicines that may increase or say goodbye of glyburide on lowering your blood sugar levels. Tell your medical professional about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal products. Do not begin a new medication without telling your physician.


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