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Precautions

Do NOT use Paxil if:

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• you happen to be allergic to the ingredient in Paxil

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• you are taking or took linezolid, a monoamine oxidase inhibitor (MAOI) (eg, phenelzine), selegiline, or St. John's wort in the last 14 days

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• you are taking a fenfluramine derivative (eg, dexfenfluramine), nefazodone, pimozide, a serotonin norepinephrine reuptake inhibitor (SNRI) (eg, venlafaxine), another SSRI (eg, fluoxetine), sibutramine, thioridazine, or tryptophan.

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Contact your physician or doctor straight away if all of these apply to you.

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Some health concerns may talk with Paxil. Tell your doctor or pharmacist if you have any medical conditions, particularly if any of the following sign up for you:

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• if you are pregnant, about to become pregnant, or are breast-feeding

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• if you consider any prescription or nonprescription medicine, herbal preparation, or dietary supplement

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• in case you have allergies to medicines, foods, or any other substances

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• if you or possibly a loved one carries a good reputation for bipolar disorder (manic-depression), other mental or mood problems, suicidal thoughts or attempts, or alcohol or substance abuse
• when you have a history of seizures, heart related illnesses, liver problems, severe kidney problems, stomach or bowel bleeding, narrow-angle glaucoma, diabetes, or metabolism problems

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• if you might be dehydrated, have low blood sodium levels, or drink alcohol

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• if you will end up having electroconvulsive therapy (ECT).

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Some medicines may interact with Paxil. Tell your doctor if you are taking some other medicines, especially any in the following:

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• Anorexiants (eg, phentermine), cimetidine, fenfluramine derivatives (eg, dexfenfluramine), linezolid, lithium, MAOIs (eg, phenelzine), metoclopramide, nefazodone, selegiline, serotonin 5-HT₁ receptor agonists (eg, sumatriptan), sibutramine, SNRIs (eg, venlafaxine), another SSRI (eg, fluoxetine), St. John's wort, tramadol, trazodone, or tryptophan because severe unwanted side effects, for instance a reaction that could include fever, rigid muscles, hypertension changes, mental changes, confusion, irritability, agitation, delirium, or coma, may occur

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• Anticoagulants (eg, warfarin), aspirin, or nonsteroidal anti-inflammatory drugs (NSAIDs) (eg, ibuprofen) for the reason that chance of bleeding, including stomach bleeding, may be increased

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• Diuretics (eg, furosemide, hydrochlorothiazide) as the probability of low blood sodium levels could be increased

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• Antiarrhythmics (eg, flecainide, propafenone, quinidine), H₁ antagonists (eg, astemizole, terfenadine), or phenothiazines (eg, chlorpromazine, thioridazine) because severe cardiovascular disease, including irregular heartbeat, may occur
• Cyproheptadine, HIV protease inhibitors (eg, ritonavir), phenobarbital, or phenytoin given that they may decrease Paxil's effectiveness

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• Aripiprazole, atomoxetine, clozapine, fluoxetine, pimozide, procyclidine, risperidone, theophylline, or tricyclic antidepressants (eg, amitriptyline) because the likelihood of their negative effects could be increased by Paxil

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• Digoxin or tamoxifen as their effectiveness might be decreased by Paxil.

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This may not be a whole listing of all interactions which could occur. Ask your doctor if Paxil may interact with other medicines that you just take. Check together with your health care provider prior to starting, stop, or affect the dose of any medicine.

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Important safety information:

• Paxil may cause drowsiness, dizziness, or blurred vision. These effects might be worse if you go on it with alcohol or certain medicines. Use Paxil with caution. Do not drive or perform other possible unsafe tasks and soon you know how you react to it.

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• Do not are drinking alcohol while you consider Paxil.

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• Check using your doctor before you use medicines that could potentially cause drowsiness (eg, sleep aids, muscle relaxers) while you are using Paxil; it may well help to increase their effects. Ask the pharmacist if you have queries about which medicines may cause drowsiness.

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• Several weeks may pass before your symptoms improve. Do NOT take over the recommended dose, alter your dose, or use Paxil more than prescribed without checking along with your doctor.

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• Children, teenagers, and the younger generation who take Paxil might be at increased risk for suicidal thoughts or actions. Closely watch all patients taking Paxil. Contact the physician at the same time if new, worsened, or sudden symptoms like depressed mood; anxious, restless, or irritable behavior; panic and anxiety attacks; or any unusual alternation in mood or behavior occur. Contact a doctor without delay if any warning signs of suicidal thoughts or actions occur.
• If your physician lets you know to prevent taking Paxil, you will need to await weeks before commencing to consider certain other medicines (eg, MAOIs, nefazodone). Ask your physician when you should start to look at your new medicines after you've got stopped taking Paxil.

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• Paxil may rarely cause a prolonged, painful erection. This could happen even when you're not making love. If this is not treated straight away, it could cause permanent sexual dysfunctions for example impotence. Contact your medical professional immediately in such a circumstance.

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• Serotonin syndrome can be a possibly fatal syndrome which can be brought on by Paxil. Your risk could be greater if you take Paxil with certain other medicines (eg, "triptans," MAOIs). Symptoms can include agitation; confusion; hallucinations; coma; fever; fast or irregular heartbeat; tremor; hyperhidrosis; and nausea, vomiting, or diarrhea. Contact your physician at once if you have these symptoms.

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• Neuroleptic malignant syndrome (NMS) is a possibly fatal syndrome that could be due to Paxil. Your risk might be greater if Paxil is utilized with certain other medicines called antipsychotics (eg, aripiprazole, risperidone). Symptoms may be much like serotonin syndrome and may include fever, rigid muscles, hypertension changes, and mental changes. Contact your doctor at once in case you have some of these symptoms.

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• Use Paxil with caution inside elderly; they might be more understanding of its effects, especially low blood sodium levels.

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• Caution is advised when working with Paxil in youngsters; they might be more understanding of its effects, especially increased risk of suicidal thoughts and actions.

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• Paxil could potentially cause weight changes. Children and teenagers might need regular weight and growth checks while they take Paxil.

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• Pregnancy and breast-feeding: Paxil could potentially cause injury to the fetus. If you become pregnant, contact your doctor. You will need to discuss the huge benefits and perils of using Paxil while you are pregnant. Paxil can be found in breast milk. If you might be or will be breast-feeding whilst you use Paxil, check with your doctor. Discuss any possible risks in your baby.

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