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Precautions

Do NOT use Paxil if:

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• you consider or have taken linezolid, a monoamine oxidase inhibitor (MAOI) (eg, phenelzine), selegiline, or St. John's wort within the past 14 days

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• you consider a fenfluramine derivative (eg, dexfenfluramine), nefazodone, pimozide, a serotonin norepinephrine reuptake inhibitor (SNRI) (eg, venlafaxine), another SSRI (eg, fluoxetine), sibutramine, thioridazine, or tryptophan.

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Contact your medical professional or doctor straight away if all of these sign up for you.

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Some health concerns may talk with Paxil. Tell your medical professional or pharmacist in case you have any health conditions, particularly if any of the following affect you:

• if you are pregnant, intending to get pregnant, or are breast-feeding

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• if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
• in case you have allergies to medicines, foods, and other substances
• if you or a member of the family features a good bipolar disorder (manic-depression), other mental or mood problems, suicidal thoughts or attempts, or alcohol or substance abuse

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• if you have a reputation seizures, heart problems, liver problems, severe kidney problems, stomach or bowel bleeding, narrow-angle glaucoma, diabetes, or metabolism problems

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• if you will be having electroconvulsive therapy (ECT).

Some medicines may talk with Paxil. Tell your doctor if you are taking any other medicines, especially any in the following:

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• Anorexiants (eg, phentermine), cimetidine, fenfluramine derivatives (eg, dexfenfluramine), linezolid, lithium, MAOIs (eg, phenelzine), metoclopramide, nefazodone, selegiline, serotonin 5-HT₁ receptor agonists (eg, sumatriptan), sibutramine, SNRIs (eg, venlafaxine), another SSRI (eg, fluoxetine), St. John's wort, tramadol, trazodone, or tryptophan because severe side effects, say for example a reaction that may include fever, rigid muscles, blood pressure level changes, mental changes, confusion, irritability, agitation, delirium, or coma, may occur
• Anticoagulants (eg, warfarin), aspirin, or nonsteroidal anti-inflammatory drugs (NSAIDs) (eg, ibuprofen) because the probability of bleeding, including stomach bleeding, could possibly be increased

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• Diuretics (eg, furosemide, hydrochlorothiazide) for the reason that probability of low blood sodium levels could possibly be increased
• Antiarrhythmics (eg, flecainide, propafenone, quinidine), H₁ antagonists (eg, astemizole, terfenadine), or phenothiazines (eg, chlorpromazine, thioridazine) because severe heart disease, including irregular heartbeat, may occur

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• Cyproheptadine, HIV protease inhibitors (eg, ritonavir), phenobarbital, or phenytoin simply because they may decrease Paxil's effectiveness

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• Aripiprazole, atomoxetine, clozapine, fluoxetine, pimozide, procyclidine, risperidone, theophylline, or tricyclic antidepressants (eg, amitriptyline) because the probability of their side effects could possibly be increased by Paxil

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• Digoxin or tamoxifen because their effectiveness could possibly be decreased by Paxil.

This may not be an entire list of all interactions that will occur. Ask your medical provider if Paxil may communicate with other medicines that you simply take. Check along with your physician before starting, stop, or affect the dose of any medicine.

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Important safety information:

• Paxil could cause drowsiness, dizziness, or blurred vision. These effects may be worse if you get it with alcohol or certain medicines. Use Paxil with caution. Do not drive or perform other possible unsafe tasks unless you recognize how you react to it.

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• Do not are drinking alcoholic beverages as you consider Paxil.

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• Check using your doctor before you use medicines that could cause drowsiness (eg, sleep aids, muscle relaxers) while you might be using Paxil; it could help to increase their effects. Ask the pharmacist if you have questions about which medicines may cause drowsiness.

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• Several weeks may pass before your symptoms improve. Do NOT take over the recommended dose, change your dose, or use Paxil more than prescribed without checking with your doctor.

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• Children, teenagers, and young adults having Paxil could be at increased risk for suicidal thoughts or actions. Closely watch all patients who take Paxil. Contact a doctor simultaneously if new, worsened, or sudden symptoms such as depressed mood; anxious, restless, or irritable behavior; anxiety attacks; or any unusual difference in mood or behavior occur. Contact the doctor right away if any warning signs of suicidal thoughts or actions occur.

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• If your medical professional lets you know to prevent taking Paxil, you will have to wait for a few months before beginning to consider certain other medicines (eg, MAOIs, nefazodone). Ask your doctor when you should start to take your medicines after you've stopped taking Paxil.
• Paxil may rarely create a prolonged, painful erection. This could happen even when you might be not having sex. If this is not treated straight away, it could possibly bring about permanent sexual dysfunctions for example impotence. Contact your physician without delay should this happen.

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• Serotonin syndrome is a possibly fatal syndrome that may be a result of Paxil. Your risk may be greater invest the Paxil with certain other medicines (eg, "triptans," MAOIs). Symptoms can include agitation; confusion; hallucinations; coma; fever; fast or irregular heartbeat; tremor; excessive sweating; and nausea, vomiting, or diarrhea. Contact your physician simultaneously when you have any of these symptoms.

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• Neuroleptic malignant syndrome (NMS) is really a possibly fatal syndrome which can be due to Paxil. Your risk could possibly be greater if Paxil is used with certain other medicines called antipsychotics (eg, aripiprazole, risperidone). Symptoms could possibly be much like serotonin syndrome and can sometimes include fever, rigid muscles, hypertension changes, and mental changes. Contact your medical professional at once in case you have some of these symptoms.

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• Use Paxil with caution inside elderly; they could possibly be more understanding of its effects, especially low blood sodium levels.

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• Caution is advised when using Paxil in youngsters; they could be more responsive to its effects, especially increased chance of suicidal thoughts and actions.
• Paxil may cause weight changes. Children and teenagers may require regular weight and growth checks since they take Paxil.

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• Pregnancy and breast-feeding: Paxil may cause trouble for the fetus. If you get pregnant, get hold of your doctor. You will need to discuss the benefits and perils associated with using Paxil while you happen to be pregnant. Paxil is situated in breast milk. If you're or is going to be breast-feeding when you use Paxil, check using your doctor. Discuss any possible risks to your baby.

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