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Uses

INDICATIONS

Prandin (repaglinide) can be an oral diabetes medicine that can help control glucose levels. This medication lowers blood sugar by resulting in the pancreas to create insulin.

Prandin is used together with dieting and exercise to help remedy diabetes type 2 symptoms. Other diabetes medicines are sometimes found in in conjunction with repaglinide as needed.

Prandin may aso be utilized for purposes unpublished in this medication guide.

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INSTRUCTIONS  

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Take Prandin exactly as prescribed by your doctor. Do not take in larger or smaller amounts or for longer than recommended. Follow the directions on your prescription label.

Prandin is generally taken 2 to 4 times daily, within thirty minutes before eating lunch. Follow a medical expert's instructions. If you skip meals, do not take on your dose of Prandin. Wait until your next meal.

Your blood glucose must be checked often, and you may need other blood tests for your doctor's office. Visit your physician regularly.

Know signs of low blood glucose levels (hypoglycemia) and how to recognize them: headache, hunger, weakness, sweating, tremor, irritability, or trouble concentrating.

Always keep a supply of sugar available in case you've got the signs of low blood glucose. Sugar sources include orange juice, glucose gel, candy, or milk. If you might have severe hypoglycemia and cannot eat or drink, make use of an injection of glucagon. Your doctor can provide a prescription for any glucagon emergency injection kit and tell you the way to give the injection.

Also await indications of blood glucose levels which is too high (hyperglycemia). These symptoms include increased thirst, increased urination, hunger, dry mouth, fruity breath odor, drowsiness, dry skin, blurred vision, and weight loss.

Check your blood glucose carefully within a time of stress or illness, in the event you travel, exercise more than usual, are drinking alcohol, or skip meals. These things may affect your glucose levels along with your dose needs might also change.

Your doctor might prefer you to stop taking Prandin for a short time in case you get sick, have a fever or infection, or if you've surgical treatment or a medical emergency.

Ask your physician how you can adjust your Prandin dose if needed. Do not change your medication dose or schedule without a medical expert's advice.

Prandin is merely a part of a total program of treatment that also includes diet, exercise, and weight management. Follow what you eat, medication, and use routines very closely. Changing these factors can affect your glucose levels.

Use Prandin regularly to have the most benefit. Get your prescription refilled before you run out of drugs completely.

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Active ingredient: Repaglinide

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Repaglinide can be a white to off-white powder with molecular formula C27 H36 N2 O4 as well as a molecular weight of 452.6. PRANDIN tablets contain 0.5 mg, 1 mg, or 2 mg of repaglinide. In addition each tablet has the following inactive ingredients: calcium hydrogen phosphate (anhydrous), microcrystalline cellulose, maize starch, polacrilin potassium, povidone, glycerol (85%), magnesium stearate, meglumine, and poloxamer. The 1 mg and a pair of mg tablets contain iron oxides (yellow and red, respectively) as coloring agents.

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Side Effects

Weight gain, diarrhea, and joint may occur. If all of these effects persist or worsen, notify your physician or pharmacist promptly.

Remember that a medical expert has prescribed this medication while he or she has judged the benefit to you is higher than the potential risk of negative effects. Many people using prescription drugs will not have serious unwanted effects.

Repaglinide might cause low blood sugar levels (hypoglycemia) especially in the event you consider other medicines for diabetes. Consuming vast amounts of alcohol, failing to get enough calories from food, or doing unusually heavy exercise can also lead to low blood glucose. Symptoms can include chills, cold sweat, dizziness, drowsiness, shaking, fast heartbeat, weakness, headache, fainting, tingling from the hands or feet, or hunger. It is often a good habit to handle glucose tablets or gel to deal with low blood sugar levels. If you don't have these reliable types of glucose, raise your blood glucose quickly when you eat a simple way to obtain sugar including ordinary sugar, honey, candy, or drinking a glass of liquid or non-diet soda. Check with your physician or pharmacist to find out list of positive actions in case you miss meals.

Symptoms of high blood sugar levels (hyperglycemia) include thirst, increased urination, confusion, drowsiness, flushing, rapid breathing, and fruity breath odor. If these symptoms occur, tell a medical expert immediately. Your doctor should adjust your diabetes medication(s).

A serious hypersensitivity to this particular drug is rare. However, seek immediate medical attention in case you notice any of the following the signs of a serious allergic attack: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.

This is not a whole set of possible unwanted effects. If you notice other effects not listed above, contact your physician or pharmacist.

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Tell your physician about all other medications you have, especially:

cyclosporine (Gengraf, Neoral, Sandimmune);

St. John's wort;

an antibiotic for example clarithromycin (Biaxin), dalfopristin/quinupristin (Synercid), erythromycin (E.E.S., EryPed, Ery-Tab, Erythrocin, Pediazole), or telithromycin (Ketek);

an antifungal medication for example fluconazole (Diflucan), itraconazole (Sporanox), or ketoconazole (Nizoral);

a barbiturate like phenobarbital (Solfoton);

heart or blood pressure level medication for example diltiazem (Cartia, Cardizem), nicardipine (Cardene), nifedipine (Nifedical, Procardia), verapamil (Calan, Covera, Isoptin, Verelan), while others;

HIV/AIDS medicine for example delavirdine (Rescriptor), efavirenz (Sustiva, Atripla), fosamprenavir (Lexiva), indinavir (Crixivan), ritonavir (Norvir), and others;

rifabutin (Mycobutin), rifampin (Rifadin, Rifater, Rifamate), or rifapentine (Priftin); or

seizure medication such as carbamazepine (Carbatrol, Equetro, Tegretol), phenytoin (Dilantin), primidone (Mysoline), yet others.

You may be more prone to have hyperglycemia (high blood glucose levels) in case you are taking Prandin with drugs that raise blood glucose levels, including:

isoniazid;

diuretics (water pills);

steroids (prednisone and others);

phenothiazines (Compazine among others);

thyroid medicine (Synthroid and others);

birth control pills along with other hormones;

seizure medicines (Dilantin and others); and

diet pills or medicines to treat asthma, colds or allergies.

You may be more prone to have hypoglycemia (low blood glucose levels) if you consider other drugs that lower blood glucose, like:

probenecid (Benemid);

a blood thinner (warfarin, Coumadin);

some nonsteroidal anti-inflammatory drugs (NSAIDs);

aspirin and other salicylates (including Pepto-Bismol);

a blood thinner (warfarin, Coumadin, Jantoven, yet others);

sulfa drugs (Bactrim, Septra, Sulfatrim, SMX-TMP, while others);

a monoamine oxidase inhibitor (MAOI); or

other oral diabetes medications, especially acarbose (Precose), metformin (Glucophage), miglitol (Glyset), pioglitazone (Actos, Duetact, Actoplus Met), or rosiglitazone (Avandia, Avandaryl, Avandamet).

These lists are certainly not complete and there a wide range of other medicines that can increase or say goodbye of Prandin on reducing your blood glucose. Using certain medicines will make it more difficult for one to tell when you have low blood glucose levels. Tell your doctor about all medications you have. This includes prescription, over-the-counter, vitamin, and herbal products. Do not begin a new medication without telling your doctor.

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Precautions

Do not use Prandin if you are allergic to repaglinide, if you've got type 1 diabetes, or if you are in a state of diabetic ketoacidosis (call your medical professional for treatment with insulin). You should not use Prandin as well as gemfibrozil (Lopid) or NPH insulin (such as isophane insulin).

Before taking repaglinide, tell your physician or pharmacist in case you are allergic into it; or if you might have another allergies. This product may contain inactive ingredients, which may cause allergy symptoms or any other problems. Talk to your pharmacist for more details. 

Before using prescription drugs, tell your doctor or pharmacist your track record, especially of: kidney disease, liver disease.

You can experience blurred vision, dizziness, or drowsiness as a result of extremely low or high blood glucose levels. Do not drive, use machinery, or go activity that requires alertness or clear vision until you are sure you are able to perform such activities safely.

Limit alcohol while taking medicines since it can increase potential risk of developing low blood sugar.

During times during the stress, like fever, infection, injury, or surgery, it could possibly be tougher to manage your blood sugar levels. Consult your medical professional because increased stress may necessitate a change in your plan of action, medications, or blood glucose testing.

During pregnancy this medication should provide only when clearly needed. Pregnancy could potentially cause or worsen diabetes. Discuss an agenda with your medical professional for managing your blood sugar levels while pregnant. Your doctor may alter your diabetes treatment during your pregnancy. Discuss the risks and benefits of different treatments (such as diet, exercise, and medications including insulin).

FDA pregnancy category C. It is not known whether Prandin will harm an unborn baby. Tell your physician in the event you are pregnant or prefer to become pregnant with all the Prandin. It is not known whether repaglinide passes into breast milk or if it may be damaging to a nursing baby. You should not breast-feed while you consider Prandin.

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