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This combination medication can be used to treat symptoms of Parkinson's disease or symptoms that are parkinson-likesuch as shakiness, stiffness, difficulty moving). Parkinson's disease is thought to be caused by too little of a substance that is naturally occurringdopamine) in the mind. Levodopa changes into dopamine in the mind, helping to control movement. Carbidopa stops the breakdown of levodopa in the bloodstream so more levodopa can enter mental performance. Carbidopa can additionally reduce some of levodopa's side effects such as for example vomiting and nausea.

Just how to use Sinemet

Take this medication by lips with or without food as directed by your doctor, usually three to four times a day.

Taking this medication with food might help to decrease nausea. It is best to avoid a diet that is high-proteinit decreases the number of levodopa your body takes in) during treatment, unless directed otherwise by the doctor. Separate your dose with this medication by since many hours as possible from any iron supplements or products containing iron (such as multivitamins with minerals) you may take. Iron can reduce the amount of this medication absorbed by the body. Consult your pharmacist or doctor for lots more details.

The dosage relies on your medical condition and response to treatment. To reduce your risk of side effects, your doctor may direct you to start this medication at a low dose and gradually increase your dose. Follow your physician's directions carefully. This combination medication comes in various strengths with different amounts of levodopa and carbidopa in each tablet. Be sure you have the correct strength of both drugs. Your doctor might also alone prescribe carbidopa to be taken with this combination.

Utilize this medication regularly to get the most benefit from it. To help you remember, take it at the same times each day.

Some patients may experience a "wearing-off" (worsening of symptoms) prior to the next dose is due. An "on-off" effect might also happen, in which unexpected short periods of stiffness occur. If these effects occur, contact your physician for possible dosage adjustments that could help to lessen this effect.

Do not stop taking this medication without consulting your physician. Some conditions could become worse whenever this drug is quickly reduced or suddenly stopped. Your dose may gradually need to be reduced. (See also adverse Effects part.)

Tell your doctor if the condition doesn't improve or if it worsens.

Side Effects

Dizziness, lightheadedness, nausea, vomiting, loss of appetite, difficulty sleeping, unusual dreams, or headache may take place. If any of these effects persist or worsen, tell your doctor or pharmacist quickly.

This medication may cause saliva, urine, or sweat to turn a dark color. This impact is harmless, but your clothes are stained.

To lessen the risk of dizziness and lightheadedness, get fully up slowly when rising from a sitting or position that is lying.

Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.

Some people taking this medication have fallen asleep abruptly during their usual activities that are dailysuch as talking on the phone, driving). In some full instances, sleep occurred without any feelings of drowsiness in advance. This sleep impact may occur anytime during therapy with carbidopa/levodopa even if you used this medication for a long time. Until you have discussed this effect with your doctor if you experience increased sleepiness or fall asleep during the day, do not drive or do other possibly dangerous activities. Your danger with this sleep impact is increased by using liquor or other medicines that will allow you to drowsy. See also Precautions section.

Tell your physician straight away if you have any serious side effects, including: new/worsening movements you can't control/spasms, greatly increased eye blinking/twitching, fainting, vision changes (such as blurred vision, double vision), eye pain, severe stomach/abdominal pain, black/tarry stools, vomit that looks like coffee grounds, mental/mood changes (such as agitation, hallucinations, depression, thoughts of suicide), signs of infection (such as sore throat that doesn't go away), easy bleeding/bruising, unusual tiredness, tingling of the hands/feet, unusual strong urges (such as increased gambling, increased sexual urges).

Get help that is medical away if you have actually any very severe side impacts, including: upper body pain.

Suddenly stopping or reducing the dose of this medication may seldom cause a tremendously condition that is serious neuroleptic malignant syndrome (NMS). Get medical help right away when you have any of the following symptoms: fever, unusual muscle mass tightness, severe confusion, perspiring, fast/irregular heartbeat, quick breathing.

a really serious allergic reaction to this drug is rare. However, get help that is medical away in the event that you notice any observeable symptoms of a serious allergic reaction, including: rash, itching/swelling (especially regarding the face/tongue/throat), serious dizziness, trouble respiration.

This is perhaps not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.

In the united states -

Call your physician for medical advice about adverse effects. You could report effects that are side FDA at 1-800-FDA-1088 or at

In Canada - Call your medical practitioner for medical advice about side effects. You may report adverse effects to Health Canada at 1-866-234-2345.


Before using this medication, tell your doctor or pharmacist if you have any other allergies if you are allergic to carbidopa or levodopa; or. This product may contain ingredients that are inactive which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

Before by using this medicine, tell your doctor or pharmacist your medical history, especially of: liver disease, glaucoma, breathing problems (such as asthma), heart disease (such as for instance heart attack, irregular heartbeat), kidney condition, stomach/intestinal ulcer, mental/mood disorders (such as for instance depression, schizophrenia), blood problems, seizures, sleep disorders.

This drug may make you dizzy or drowsy. Do not drive, use machinery, or do any activity that requires alertness you can perform such activities safely until you are sure. Limit alcoholic beverages. See also Side Effects part.

Before having surgery, tell your doctor or dentist about all the products you use (including prescription drugs, nonprescription drugs, and natural products).

During pregnancy, this medication should be utilized only when obviously needed. Discuss the risks and benefits with your physician.

Levodopa passes into breast milk. It really is unknown if carbidopa passes into breast milk. Consult your medical practitioner before breast-feeding.

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