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INDICATIONSLevodopa is changed into a chemical called dopamine (DOE pa meen) inside brain. Symptoms of Parkinson's disease might be a result of low levels of dopamine in the brain.

Carbidopa helps prevent the breakdown of levodopa before it can achieve the brain and work.

The mixture of carbidopa and levodopa is employed to help remedy Parkinson symptoms for example muscle stiffness, tremors, spasms, and poor muscle control. This medication is also used to deal with Parkinson symptoms caused by deadly carbon monoxide poisoning or manganese intoxication.

Carbidopa and levodopa could also be used for other purposes unlisted in this medication guide.

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If you might be already taking levodopa (Larodopa, Dopar), you need to stop taking it a minimum of 12 hours before starting taking carbidopa and levodopa.

Take just as prescribed through your doctor. Do not take in larger or smaller amounts or for over recommended. Follow the directions in your prescription label.

Carbidopa and levodopa might be taken with or without food. Take your doses at regular intervals to help keep a stable quantity of the drug inside you at all times.
Do not crush, chew, or break an extended-release tablet. Swallow the pill whole. Breaking or opening the pill could potentially cause excessive drug to be removed in the past.

The regular tablet could be broken or crushed as required to make it easier to swallow.

To consider the orally disintegrating tablet (Parcopa):

Keep the tablet in its blister pack until you are ready to make medicine. Open the package and peel back the foil from named blister. Do not push a tablet with the foil or you may damage today.

Using dry hands, remove these days and place it in your mouth. It will start to dissolve right away.

Do not swallow the tablet whole. Allow it to dissolve within your mouth without chewing. Swallow many times as the tablet dissolves.
It may take as much as weeks utilizing carbidopa and levodopa before your symptoms improve. For best results, keep using the medication as directed. Talk with your medical professional in case your symptoms tend not to improve right after weeks of treatment. Also inform your doctor if the connection between prescription drugs appear to wear off quickly among doses.

To make sure this medicine is helping your condition and is not causing harmful effects, your blood must be tested often. Your heart, liver, and kidney function might also should be tested. Visit your medical professional regularly.

This medication may cause unusual results with certain medical tests. Tell any doctor who treats you that you happen to be using carbidopa and levodopa.


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Store at room temperature far from moisture, heat, and lightweight.


Active Ingredient: Carbidopa and Levodopa

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Side Effects

You may observe that your sweat, urine, or saliva appears dark in color, for example red, brown, or black. This is not a harmful unwanted effect, nonetheless it could potentially cause staining of the clothes or bed linens.
Get emergency medical help if you have these warning signs of a hypersensitivity: hives; lack of breath; swelling of one's face, lips, tongue, or throat. Call your medical professional at once for those who have all of these serious unwanted side effects:

restless muscle movements inside your eyes, tongue, jaw, or neck;

worsening of tremors (uncontrolled shaking);

high fever, stiff muscles, sweating, fast or uneven heartbeats, rapid breathing, feeling as you might distribute;

seizure (convulsions);

painful or difficult urination;

severe nausea, vomiting, or diarrhea;

uneven heartrate or fluttering with your chest;

confusion, hallucinations, anxiety, agitation, depressed mood, thoughts of suicide or hurting yourself;

chest pain or heavy feeling, pain spreading to the arm or shoulder.

Less serious unwanted side effects can include:

mild nausea, dry mouth, decrease of appetite, heartburn, diarrhea, constipation;

headache, dizziness, drowsiness, blurred vision;

sneezing, stuffy nose, cough, or any other cold symptoms;

sleep problems (insomnia), strange dreams;

muscle pain, numbness or tingly feeling; or

skin rash or itching.

This is not a complete listing of unwanted side effects and others may occur. Call your doctor for medical health advice about side effects.

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Do not take carbidopa and levodopa if you have used an MAO inhibitor for example isocarboxazid (Marplan), phenelzine (Nardil), or tranylcypromine (Parnate) within the past two weeks. Serious, life-threatening unwanted side effects can happen for carbidopa and levodopa before the MAO inhibitor has cleared from your body. 

You shouldn't take medicines if you're allergic to carbidopa (Lodosyn) or levodopa (Larodopa), or if you have:

narrow-angle glaucoma;

unusual skin lesions which may have not been checked by the doctor; or

a good reputation for malignant melanoma (cancer of the skin).

If you've some of these other concerns, you may need a dose adjustment or special tests:

heart disease, high blood pressure levels, coronary heart, a heart rhythm disorder, or possibly a prior cardiac event;

asthma, chronic obstructive pulmonary disease (COPD), or any other breathing disorder;
liver or kidney disease;

an endocrine (hormonal) disease;

a stomach or intestinal ulcer;

wide-angle glaucoma; or

depression or any other mental illness.
Carbidopa and levodopa may cause you to get to sleep during normal daytime activities for example working, talking, eating, or driving. You may drift off suddenly, even with feeling alert. Tell your physician for those who have any issues with daytime sleepiness or drowsiness.

You could have increased sexual urges, unusual urges to gamble, or another intense urges while taking carbidopa and levodopa. It is not known perhaps the medicine actually causes this effect. Talk with your medical professional if you feel you might have any intense or unusual urges while taking carbidopa and levodopa.

Some people taking medicines for Parkinson's disease have developed skin cancer (melanoma). However, individuals with Parkinson's disease could have a and the higher chances than most people for developing melanoma. Talk to your doctor about your specific risk and what skin symptoms to view for. You may need to have regular skin exams.
FDA pregnancy category C. It is not known whether carbidopa and levodopa will harm an unborn baby. Tell your physician if you happen to be pregnant or want to get pregnant while using medicines. Carbidopa and levodopa may pass into breast milk and can harm a nursing baby. Do not use this medication without telling a medical expert if you happen to be breast-feeding a baby.

The disintegrating tablet (such as Parcopa) could have phenylalanine. Talk to a medical expert before employing this kind of carbidopa and levodopa in case you have phenylketonuria (PKU).

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If you missed the dose go on it once you remember. Skip the missed dose if it is almost time for your upcoming scheduled dose. Do not take extra medicine to produce inside the missed dose.


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