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INDICATIONSLevodopa is transformed into a chemical called dopamine (DOE pa meen) in the brain. Symptoms of Parkinson's disease might be caused by 'abnormal' amounts of dopamine in the brain.

Carbidopa stops the breakdown of levodopa before it may get to the brain and be effective.

The mix of carbidopa and levodopa is employed to treat Parkinson symptoms including muscle stiffness, tremors, spasms, and poor muscle control. This medication can be used to help remedy Parkinson symptoms caused by co poisoning or manganese intoxication.

Carbidopa and levodopa may also be used for other purposes unpublished with this medication guide.


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If you happen to be already taking levodopa (Larodopa, Dopar), you have to stop taking it at least 12 hours prior to starting taking carbidopa and levodopa.

Take exactly as prescribed because of your doctor. Do not take in larger or smaller amounts or for longer than recommended. Follow the directions on the prescription label.

Carbidopa and levodopa can be taken with or without food. Take your doses at regular intervals to hold a comfortable volume of the drug within you at all times.
Do not crush, chew, or break an extended-release tablet. Swallow the pill whole. Breaking or opening the pill might cause excessive drug to be removed at one time.

The regular tablet could be broken or crushed as required to make it easier to swallow.

To take the orally disintegrating tablet (Parcopa):

Keep the tablet rolling around in its blister pack until you're ready to take the medicine. Open the package and peel back the foil from today blister. Do not push a tablet through the foil or you may damage today.

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Using dry hands, remove today and place it inside your mouth. It will commence to dissolve right away.

Do not swallow today whole. Allow it to dissolve within your mouth without chewing. Swallow repeatedly as these days dissolves.
It may take up to weeks of utilizing carbidopa and levodopa before your symptoms improve. For best results, keep with all the medication as directed. Talk with a medical expert in case your symptoms usually do not improve soon after weeks of treatment. Also tell your doctor when the connection between prescription drugs appear to wear off quickly between doses.

To make certain this medicine is helping your condition and is not causing harmful effects, your blood should be tested often. Your heart, liver, and kidney function can also need to be tested. Visit your medical professional regularly.

This medication can cause unusual results with certain lab tests. Tell any doctor who treats you that you are using carbidopa and levodopa.

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Store at room temperature from moisture, heat, and lightweight.

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Active Ingredient: Carbidopa and Levodopa

Side Effects

You may realize that your sweat, urine, or saliva appears dark in color, for example red, brown, or black. This is not a harmful side-effect, however it may cause staining of the clothes or bed linens.
Get emergency medical help when you have some of these indications of a hypersensitivity: hives; breathlessness; swelling of your respective face, lips, tongue, or throat. Call a medical expert simultaneously in case you have all of these serious unwanted side effects:

restless muscle movements inside your eyes, tongue, jaw, or neck;

worsening of tremors (uncontrolled shaking);

high fever, stiff muscles, sweating, fast or uneven heartbeats, rapid breathing, feeling just like you might pass out;

seizure (convulsions);

painful or difficult urination;

severe nausea, vomiting, or diarrhea;

uneven heartrate or fluttering within your chest;

confusion, hallucinations, anxiety, agitation, depressed mood, thoughts of suicide or hurting yourself;

chest pain or heavy feeling, pain spreading for the arm or shoulder.

Less serious side effects can sometimes include:

mild nausea, dry mouth, loss in appetite, heartburn, diarrhea, constipation;

headache, dizziness, drowsiness, blurred vision;

sneezing, stuffy nose, cough, or another cold symptoms;

sleep problems (insomnia), strange dreams;

muscle pain, numbness or tingly feeling; or

skin rash or itching.

This is not a complete listing of unwanted side effects among others may occur. Call your physician for medical advice about negative effects.

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Do not take carbidopa and levodopa when you have used an MAO inhibitor such as isocarboxazid (Marplan), phenelzine (Nardil), or tranylcypromine (Parnate) within the past 14 days. Serious, life-threatening unwanted side effects can occur for carbidopa and levodopa prior to the MAO inhibitor has cleared from a body. 

You must not take this medication if you're allergic to carbidopa (Lodosyn) or levodopa (Larodopa), or when you have:

narrow-angle glaucoma;

unusual wounds which may have not been checked by way of a doctor; or

a reputation malignant melanoma (skin cancer).

If you might have all of these other difficulties, you may need a dose adjustment or special tests:

heart disease, high blood pressure, heart disease, a heart rhythm disorder, or even a prior cardiac arrest;

asthma, chronic obstructive pulmonary disease (COPD), or any other breathing disorder;
liver or kidney disease;

an endocrine (hormonal) disease;

a stomach or intestinal ulcer;

wide-angle glaucoma; or

depression or another mental illness.
Carbidopa and levodopa could potentially cause you to go to sleep during normal daytime activities including working, talking, eating, or driving. You may get to sleep suddenly, despite feeling alert. Tell your physician for those who have any problems with daytime sleepiness or drowsiness.

You might have increased sexual urges, unusual urges to gamble, or another intense urges while taking carbidopa and levodopa. It is not known whether the medicine actually causes this effect. Talk with your medical professional if you feel you've any intense or unusual urges while taking carbidopa and levodopa.

Some people taking medicines for Parkinson's disease allow us skin cancer (melanoma). However, people who have Parkinson's disease may have a and the higher chances than most people for developing melanoma. Talk to a medical expert about your specific risk and what skin symptoms to observe for. You may need to have regular skin exams.
FDA pregnancy category C. It is not known whether carbidopa and levodopa will harm an baby. Tell a medical expert if you happen to be pregnant or intend to conceive while using the prescription drugs. Carbidopa and levodopa may pass into breast milk and may harm a nursing baby. Do not use medicines without telling your physician if you happen to be breast-feeding a child.

The disintegrating tablet (for example Parcopa) could have phenylalanine. Talk to your doctor before using this way of carbidopa and levodopa if you have phenylketonuria (PKU).

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If you missed the dose go when you remember. Skip the missed dose if it's almost time for your upcoming scheduled dose. Do not take extra medicine to generate in the missed dose.

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