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Tofranil (Imipramine) is at a small grouping of drugs called tricyclic antidepressants. Imipramine affects chemicals inside the brain that may become unbalanced.
It is utilized to take care of the signs of depression.
This medicine may also be used for purposes besides those placed in medicines guide.


Take this medication exactly as it had been prescribed for you. Do not take the medication in larger amounts, or take it more than recommended through your doctor. Your doctor may occasionally improve your dose to successfully obtain the best comes from medicines. Follow the directions on the prescription label.
If you must have any kind of surgery, tell the surgeon before hand you are taking imipramine. You may need to stop with all the medicine for the short period of time.
Do not stop using imipramine without first talking to your doctor. You may need to use much less before you stop the medication completely. Stopping this medication suddenly may cause one to have unpleasant side effects. It may take around 21 days of utilizing this medicine before your symptoms improve. For best results, keep using the medication as directed. Talk with a medical expert should your symptoms do not improve after 25 days of treatment.

If you missed the dose go on it when you remember. If it really is almost time for your next dose, skip the missed dose and consider the medicine with the next regularly scheduled time. Do not take extra medicine to make up the missed dose.

Seek emergency medical help if you think you have used an excessive amount of this medicine. An overdose of imipramine could be fatal.
Symptoms of the imipramine overdose may include uneven heartbeats, extreme drowsiness, agitation, vomiting, blurred vision, sweating, muscle stiffness, swelling, shortness of breath, blue lips or fingernails, feeling light-headed, fainting, seizure (convulsions), or coma.

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Take this medicine as prescribed through your doctor.


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Store imipramine at room temperature faraway from moisture and heat.


Active Ingredient: Imipramine

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Tofranil is a tricyclic antidepressant. It works by improving the activity of certain chemicals inside brain that really help elevate mood.

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Side Effects

Get emergency medical help if you've all of these signs associated with an allergic reaction: hives; lack of breath; swelling of one's face, lips, tongue, or throat.

Call your doctor immediately if you've got any new or worsening symptoms like: mood or behavior changes, anxiety, panic attacks, sleep disorders, or if you are feeling impulsive, irritable, agitated, hostile, aggressive, restless, hyperactive (mentally or physically), more depressed, or have thoughts about suicide or hurting yourself.

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Call your physician at once if you've got any of these serious negative effects:

fast, pounding, or uneven heart rate;

chest pain or heavy feeling, pain spreading towards the arm or shoulder, nausea, sweating, general ill feeling;

sudden numbness or weakness, especially somewhere in the body;

sudden headache, confusion, difficulties with vision, speech, or balance;

feeling lacking breath, despite having mild exertion;

swelling, rapid putting on weight;

confusion, hallucinations, or seizure (convulsions);

easy bruising or bleeding, unusual weakness;

restless muscle movements with your eyes, tongue, jaw, or neck;

urinating more or less than usual;

extreme thirst with headache, nausea, vomiting, and weakness;

skin rash, bruising, severe tingling, numbness, pain, or muscle weakness.

Less serious side effects could possibly be very likely to occur, such as:

nausea, vomiting, stomach pain, loss in appetite;

constipation or diarrhea;

dry mouth, unpleasant taste;

weight changes;

weakness, not enough coordination;

feeling dizzy, drowsy, or tired;


blurred vision, headache, ringing with your ears;

breast swelling (in men or women); or

decreased sex drive, impotence, or difficulty owning an orgasm.

Tofranil is to be used only through the patient for whom it is prescribed. Do not share it with other people.
If your symptoms usually do not improve or if they become worse, seek advice from your doctor.

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Do not use Tofranil if:

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you might be allergic to any ingredient in Tofranil;

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you might have taken furazolidone or possibly a monoamine oxidase inhibitor (MAOI) (e.g., phenelzine) within the last two weeks, or if you adopt astemizole, droperidol, or terfenadine.

you happen to be dealing with a recently available cardiac event.
Contact your medical professional or physician right away if these sign up for you.

Some health concerns may communicate with Tofranil . Tell your medical professional or pharmacist if you might have any medical conditions, especially if any in the following affect you:

if you happen to be pregnant, likely to conceive, or are breast-feeding

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if you're taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement

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if you've got allergies to medicines, foods, or any other substances

if you drink alcohol-containing beverages daily or you've a good reputation for alcohol abuse

if you are taking thyroid medicine or you have a history of overactive thyroid, glaucoma, heart disease, kidney or liver problems, diabetes, seizures, the blood disease porphyria, or difficulty urinating

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if you have a good reputation for suicidal thoughts or behavior, bipolar disorder, or some other mental disorders; you happen to be undergoing electroshock therapy; or you are scheduled to have any surgery.

Some MEDICINES MAY INTERACT with Tofranil . Tell your health care provider if you are taking another medicines, especially any with the following:

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Azole antifungals (eg, fluconazole), cimetidine, duloxetine, flecainide, methylphenidate, mibefradil, phenothiazines (eg, chlorpromazine), propafenone, quinidine, selective serotonin reuptake inhibitors (SSRIs) (eg, fluoxetine), or terbinafine since they could raise the likelihood of Tofranil 's unwanted effects

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Arsenic, astemizole, droperidol, furazolidone, MAOIs (eg, phenelzine), pimozide, streptogramins (eg, dalfopristin), terfenadine, or tramadol because the chance of blood pressure, serious heart disease (eg, irregular heartbeat), or seizures could possibly be increased

Barbiturates (eg, phenobarbital) or phenytoin simply because they may decrease Tofranil 's effectiveness

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Anticholinergics (eg, benztropine), carbamazepine, or sympathomimetics (eg, phenylephrine) since the chance of their side effects could possibly be increased by Tofranil

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Clonidine, guanethidine, or guanfacine as their effectiveness might be decreased by Tofranil

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