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This medicine is used alone or with other medications to prevent vomiting and nausea caused by cancer drug treatment (chemotherapy) and radiation therapy. It is also used to prevent and treat nausea and vomiting after surgery. It works by blocking one of the body's normal substances (serotonin) that causes nausea.

How to utilize Zofran

To prevent nausea from chemotherapy, take this medicine by mouth usually within half an hour before treatment begins. To avoid nausea from radiation treatment, take this medicine by mouth 1 or 2 hours prior to the begin of your treatment. To prevent nausea after surgery, take ondansetron by mouth 1 hour before the beginning of surgery. This medication may be taken with or without food. However, your doctor may let you know to not consume before chemotherapy, radiation, or surgery.

If you're using the liquid form of this medication, use a special measuring spoon or device to measure out your prescribed dose. Do not use a household spoon because you may not get the correct dose.

Take any other doses as directed by your doctor. Ondansetron can be taken up to three times a for 1 to 2 days after your chemotherapy or radiation treatment is finished day. It regularly in order to get the most benefit from it if you are taking this medication on a prescribed schedule, take. To help you remember, take it at the same times each day.

Dosage relies on your medical condition and response to therapy. The dosage for children may also be based on age and weight. The usual maximum dose in patients with severe liver problems is 8 milligrams in 24 hours. Take this medication exactly as directed. Do not take more medication or take it more often than prescribed. Pose a question to your pharmacist or doctor in the event that you have concerns.

Inform your physician if your condition does not improve or if it worsens.

adverse Effects

Headache, lightheadedness, dizziness, drowsiness, tiredness, or constipation might occur. If these effects persist or worsen, notify your doctor quickly.

Keep in mind that your physician has recommended this medication she has judged that the benefit to you is greater than the risk of side effects because he or. Many people using this medication do not have serious side effects.

Tell your doctor right away if any of the not likely but severe negative effects happen: stomach pain, muscle spasm/stiffness, eyesight modifications (age.g., temporary lack of vision, blurred vision).

Get medical help right away if any of these rare but very severe side effects occur: chest pain, slow/fast/irregular heartbeat, serious dizziness, fainting.

This medication may increase serotonin and rarely cause a very serious condition called serotonin syndrome/toxicity. The risk increases if you are also taking other drugs that increase serotonin, so tell your doctor or pharmacist of all the drugs you take (see Drug Interactions section). Get medical help right away if you develop some of the after symptoms: fast heartbeat, hallucinations, loss in coordination, severe dizziness, severe nausea/vomiting/diarrhea, twitching muscle tissue, unexplained fever, unusual agitation/restlessness.

an extremely serious allergic reaction to this drug is unlikely, but stop taking this medication and seek immediate medical attention if it occurs. Symptoms of a serious allergic reaction include: rash, itching/swelling (especially of the face/tongue/throat), serious dizziness, trouble breathing.

This might be not a complete list of possible adverse effects. If you notice other effects not listed above, contact your pharmacist or doctor.

In the usa -

Call your doctor for medical advice about adverse effects. You may report adverse effects to FDA at 1-800-FDA-1088 or at

In Canada - Call your doctor for medical advice about side impacts. You may report effects that are side Health Canada at 1-866-234-2345.


Before taking ondansetron, tell your medical professional or pharmacist if you have any other allergies if you are allergic to it; or to other serotonin blockers (e.g., granisetron); or. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Speak to your pharmacist for additional information.

Before using this medicine, tell your medical professional or pharmacist your medical history, especially of: irregular heartbeat, liver infection, stomach/intestinal dilemmas (age.g., present abdominal surgery, ileus, swelling).

Ondansetron might cause a disorder that affects the heart rhythm (QT prolongation). QT prolongation can seldom cause severe (rarely fatal) fast/irregular heartbeat and other symptoms (such as for instance severe dizziness, fainting) that require medical attention straight away.

The risk of QT prolongation could be increased if you have certain medical conditions or are taking other drugs that could cause QT prolongation. Before using ondansetron, tell your physician or pharmacist of the many drugs you take and if you have any of the following conditions: certain heart disease (heart failure, sluggish heartbeat, QT prolongation into the EKG), family history of specific heart problems (QT prolongation in the EKG, sudden cardiac death).

Lower levels of potassium or magnesium in the blood may also increase your risk of QT prolongation. This risk may increase if you use certain drugs (such as diuretics/"water pills") or if you have conditions such as severe sweating, diarrhea, or vomiting. Talk to your doctor about using ondansetron properly.

This drug may make you dizzy or drowsy. Do not drive, use machinery, or do any activity that requires alertness you can perform such activities safely until you are sure. Limit alcoholic beverages.

To minimize dizziness and lightheadedness, get right up slowly whenever increasing from a sitting or position that is lying.

Older adults may be more sensitive to the side effects of this drug, especially QT prolongation (see above).

This medication should be used only when clearly needed during pregnancy. Talk about the risks and benefits together with your doctor.

It isn't known whether this drug passes into breast milk. Consult your doctor before breast-feeding.

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